421-20-5

Basic information

• Product Name: METHYL FLUOROSULFONATE
• Synonyms: fluorosulfuricacid,methylester;Fluorosulfuricacidmethylester;magicmethyl;methylfluorosulfate;methylfluosulfonate;FLUOROSULFONIC ACID METHYL ESTER;METHYL FLUOROSULFONATE;METHYL FLUOROSULPHONATE
• CAS NO: 421-20-5
• Molecular Formula: CH₃FO₃S
• Molecular Weight: 114.1
• EINECS: 207-004-3
• Mol File: 421-20-5.mol
• Article Data: 10

Chemical Properties

• Melting Point: -95°
• Boiling Point: 93 °C
• Flash Point: 10℃
• Appearance: /liquid
• Density: 1.45
• Vapor Pressure: 57.3mmHg at 25°C
• Refractive Index: nD20 1.3326
• Merck: 6075
• CAS DataBase Reference: METHYL FLUOROSULFONATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL FLUOROSULFONATE(421-20-5)
• EPA Substance Registry System: METHYL FLUOROSULFONATE(421-20-5)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39
• RIDADR: 3265
• RTECS: LP0720000
• Hazardous Substances Data: 421-20-5(Hazardous Substances Data)

Usage

Chemical Properties

Colorless liquid; ethereal odor.

Uses

In organic synthesis as methylating agent.

Hazard

Toxic. Strong irritant to tissue, inhalationof fume must be avoided. Reacts with water, steam,and acids, evolving corrosive vapor.

InChI:InChI=1/CH3FO3S/c1-5-6(2,3)4/h1H3

Upstream product

• 186581-53-3 diazomethane 
• 534-15-6 1,1-dimethoxyethane 
• 697-18-7 tetrafluoroethane-β-sultone 
• 812-01-1 methyl chlorosulfate 
• 10186-63-7 2-fluoro-2-methoxy trifluoropropanoic acid methyl ester 
• 77-78-1 dimethyl sulfate 
• 115-10-6 Dimethyl ether 
• 7789-21-1 fluorosulphonic acid 
• 74-88-4 methyl iodide 
• 54376-60-2 2-(Trifluoromethyl)-3-methoxy-1,1,1,3,4,4,5,5,5-nonafluoropentane 
• 67-56-1 methanol 
• 1584-03-8 perfluoro-2-methylpent-2-ene 
• 67-64-1 acetone 
• 34557-54-5 methane 

Downstream Products

• 81280-27-5 3-methoxy-1,1,5,6-tetraphenyl-1H-indene 
• 81280-28-6 3-(4-methoxybutoxy)-1,1,5,6-tetraphenyl-1H-indene 
• 66730-46-9 2-benzyl-3-methyl-2-hexenal 
• 69824-28-8 [1-(3-Methylsulfanyl-propylsulfanyl)-ethoxy]-benzene 
• 69824-36-8 2-Methoxy-4-methyl-1-{(E)-4-[1-(3-methylsulfanyl-propylsulfanyl)-ethoxy]-but-2-enyloxy}-benzene 
• 69824-30-2 Benzoic acid 3-[1-(3-methylsulfanyl-propylsulfanyl)-ethoxy]-propyl ester 
• 69824-31-3 {3-[1-(3-Methylsulfanyl-propylsulfanyl)-ethoxy]-propyl}-benzene 
• 69824-34-6 [1-(2-Methylsulfanyl-ethylsulfanyl)-ethoxymethyl]-benzene 
• 69923-68-8 {3-Methyl-1-[1-(2-methylsulfanyl-ethylsulfanyl)-ethoxy]-butyl}-benzene 
• 98885-68-8 Methyldiphenyl<1-(triphenylphosphonio)cyclopropyl>phosphonium-bis(hexafluorophosphat) 

Relevant articles and documents

Method for efficiently preparing sulfuryl fluorides compound by catalytic fluorination

The invention belongs to the technical field of the chemical synthesis, and particularly relates to a method for efficiently preparing a sulfuryl fluorides compound by catalytic fluorination. The provided method for efficiently preparing the sulfuryl fluorides compound by the catalytic fluorination comprises the following steps: enabling a sulfonyl chlorides compound to react with a hydroge fluoride under the action of a catalyst of a sulfonic acids derivative, to obtain the sulfuryl fluorides compound. A novel catalytic technology is provided, and the method has extensive substrate applicability. Efficient catalytic efficiency and yield are expressed.

The chemistry of organoborates. 9. A regiospecific and highly stereoselective construction of trisubstituted αβ-unsaturated ketones, tetrasubstituted αβ-unsaturated ketones and specifically protected 1,3-diketones from alkynyltrialkylborates

Lithium alkynyltrialkylborates react with dioxolanium fluorosulphonates in a highly stereoselective fashion such that the dioxolanium group and the migrating group and the migrating group are on the same side of the new alkene intermediate. Hydrolysis of the intermediate yields Z-trisubstituted αβ-unsaturated ketones in which all three substituents have different origins and can be independently varied. Oxidation of the intermediates gives β-ketoacetals, which are regiospecifically protected 1,3-diketones. If the initial intermediates are allowed to stand, then another migration occurs and tetra-substituted αβ-unsaturated ketones result.

REACTION OF IODINE FLUOSULFATE AND TRIS(FLUOSULFATE) WITH HALOALKANES

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