32365-83-6

Usage

Chemical group

Glucofuranose derivatives

Derivative of

D-glucose

Common use

Protecting group for hydroxyl group of glucose molecule in organic synthesis

Molecular weight

220.21 g/mol

Physical state

White crystalline solid

Solubility

Soluble in water and organic solvents

Application

Protection and manipulation of glucose molecules in the synthesis of various organic compounds in carbohydrate chemistry

Upstream product

• 13109-12-1 1,2-O-isopropylidene-3,4,6-tri-O-acetyl-α-D-glucopyranoside 
• 582-52-5 1,2:5,6-diacetone-D-glucose 

Downstream Products

• 55628-55-2 1,2-O-isopropylidene-3,4,6-tri-O-benzyl-α-D-glucopyranoside 

Relevant academic research and scientific papers

Synthesis of CH2-Linked α(1,6)-Disaccharide Analogues by α-Selective Radical Coupling C-Glycosylation

C-Linked carbohydrate structure, in which the cleavable O-glycosidic linkage is replaced by a carbon unit, is a useful tool for functional analyses of glycoconjugates. We describe a synthetic method for α-CH2-linked disaccharide structures, such as Glc(1,6)-Glc, by stereoselective radical-coupling C-glycosylation between a conformationally constrained and stable C1-sp3 hybridized xanthate donor and a carefully designed acceptor.

Simple and efficient MW-assisted cleavage of acetals and ketals in pure water

Simple and efficient MW-assisted cleavage of acetal and ketal is proposed in deionized water and in a very short time.

The Reaction of N-Dichloromethylene-N,N-dialkylammonium Chlorides with Free Sugars: an Efficient Synthesis of Glycosyl Chlorides

The treatment of aldose derivatives that are protected at all but the anomeric hydroxy groups with N-dichloromethylene-N,N-dialkylammonium chlorides (alkyl = Me, Et) provides an improved method of preparing the corresponding glycosyl chlorides.Analogous derivatives containing an unprotected C1-C2 diol give 2-O-(N,N-dialkylcarbamoyl)glycosyl chlorides.