32382-66-4

Basic information

• Product Name: N-(2-methoxyethyl)aniline
• Synonyms: N-(2-methoxyethyl)aniline
• CAS NO: 32382-66-4
• Molecular Formula: C₉H₁₃NO
• Molecular Weight: 151.21
• Mol File: 32382-66-4.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(2-methoxyethyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-methoxyethyl)aniline(32382-66-4)
• EPA Substance Registry System: N-(2-methoxyethyl)aniline(32382-66-4)

Safety Data

• Hazardous Substances Data: 32382-66-4(Hazardous Substances Data)

Upstream product

• 703-56-0 N-phenyl-2-oxazolidinone 
• 124-41-4 sodium methylate 
• 10312-83-1 methoxyacetaldehyde 
• 62-53-3 aniline 
• 111-95-5 Bis-(2-methoxyethyl)amine 
• 6482-24-2 2-Bromoethyl methyl ether 
• 81090-01-9 [N-(2-methoxyethyl)-N-methyl]aniline 
• 42988-04-5 N-ethyl-N-(2-methoxyethyl)aniline 
• 24388-23-6 2-phenyl-4,4,5,5-tetramethyl-1,3,2-dioxoborole 
• 109-85-3 2-methoxyethylamine 
• 98-80-6 phenylboronic acid 
• 108-86-1 bromobenzene 
• 591-50-4 iodobenzene 
• 109-86-4 2-methoxy-ethanol 

Downstream Products

• 100141-33-1 N-(2-chloro-allyl)-N-(2-methoxy-ethyl)-aniline 
• 32382-80-2 N-(β-Methoxyaethyl)-formanilid 
• 105340-37-2 N-(2-chloro-allyl)-N-(2-methoxy-ethyl)-4-nitroso-aniline 
• 103867-28-3 3-Cyclohexyl-N-(2-methoxy-ethyl)-N-phenyl-propionamide 
• 103867-35-2 3-Cyclohexyl-N-(2-methoxy-ethyl)-2-methyl-N-phenyl-propionamide 
• 70039-93-9 {3-[(2-Methoxy-ethyl)-phenyl-carbamoyloxy]-phenyl}-carbamic acid prop-2-ynyl ester 
• 70039-90-6 {3-[(2-Methoxy-ethyl)-phenyl-carbamoyloxy]-phenyl}-carbamic acid allyl ester 
• 70039-89-3 {3-[(2-Methoxy-ethyl)-phenyl-carbamoyloxy]-phenyl}-carbamic acid isobutyl ester 
• 70039-96-2 (2-Methoxy-ethyl)-phenyl-carbamic acid 3-ethylsulfanylcarbonylamino-phenyl ester 
• 70039-81-5 N-(2-Methoxyethyl)-carbanilic acid-(3-methoxy carbonylamino)-phenyl-ester 
• 70040-14-1 (2-Methoxy-ethyl)-phenyl-carbamic acid 3-methylsulfanylcarbonylamino-phenyl ester 
• 70040-51-6 {3-[(2-Methoxy-ethyl)-phenyl-carbamoyloxy]-phenyl}-carbamic acid 2-chloro-1-methyl-ethyl ester 
• 70039-87-1 {3-[(2-Methoxy-ethyl)-phenyl-carbamoyloxy]-phenyl}-carbamic acid sec-butyl ester 
• 70039-86-0 {3-[(2-Methoxy-ethyl)-phenyl-carbamoyloxy]-phenyl}-carbamic acid isopropyl ester 

Relevant articles and documents

DIACYLGLYCEROL KINASE MODULATING COMPOUNDS

The present disclosure provides diacylglycerol kinase modulating compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors, and viral infections, such as HIV or hepatitis B virus infection. The compounds can be used alone or in combination with other agents.

Efficient methylation of anilines with methanol catalysed by cyclometalated ruthenium complexes

Cyclometalated ruthenium complexes4-10allow the effective methylation of anilines with methanol to selectively giveN-methylanilines. This hydrogen autotransfer procedure proceeds under mild conditions (60 °C) in a practical manner (NaOH as base). Mechanistic investigations suggest an active homogenous ruthenium complex and β-hydride elimination of methanol as the rate determining step.

Chan-Evans-Lam Amination of Boronic Acid Pinacol (BPin) Esters: Overcoming the Aryl Amine Problem

The Chan-Evans-Lam reaction is a valuable C-N bond forming process. However, aryl boronic acid pinacol (BPin) ester reagents can be difficult coupling partners that often deliver low yields, in particular in reactions with aryl amines. Herein, we report effective reaction conditions for the Chan-Evans-Lam amination of aryl BPin with alkyl and aryl amines. A mixed MeCN/EtOH solvent system was found to enable effective C-N bond formation using aryl amines while EtOH is not required for the coupling of alkyl amines.