32387-01-2

Basic information

• Product Name: 2-{[(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino}-1H-isoindole-1,3(2H)-dione
• CAS NO: 32387-01-2
• Molecular Formula: C₁₅H₁₀N₂O₃
• Molecular Weight: 266.2515
• Mol File: 32387-01-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 462.2°C at 760 mmHg
• Flash Point: 233.3°C
• Density: 1.44g/cm³
• Vapor Pressure: 1.01E-08mmHg at 25°C
• Refractive Index: 1.703
• CAS DataBase Reference: 2-{[(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino}-1H-isoindole-1,3(2H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{[(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino}-1H-isoindole-1,3(2H)-dione(32387-01-2)
• EPA Substance Registry System: 2-{[(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino}-1H-isoindole-1,3(2H)-dione(32387-01-2)

Safety Data

• Hazardous Substances Data: 32387-01-2(Hazardous Substances Data)

Usage

Molecular structure

The compound has an isoindole-1,3(2H)-dione core structure with a cyclohexa-2,4-dien-1-ylidene moiety and an amino group attached to a methyl group.

Biological and pharmaceutical applications

The compound has potential as an anti-cancer, anti-inflammatory, and anti-microbial agent.

Enzyme and pathway inhibition

The compound has been shown to inhibit certain enzymes and pathways involved in cancer cell proliferation and survival.

Further research needed

More research is needed to fully understand the pharmacological and biological activities of this compound and its potential as a therapeutic agent.

Upstream product

• 1875-48-5 N-aminophthalamide 
• 90-02-8 salicylaldehyde 

Downstream Products

• 93517-77-2 4-m-tolylphthalazin-1(2H)-one 
• 71271-35-7 4-(2-methoxy-phenyl)-2H-phthalazin-1-one 

Relevant articles and documents

Synthesis, characterization, antimicrobial, DNA binding, and oxidative cleavage activities of Cu(II) and Co(II) complexes with 2-(2- hydroxybenzylideneamino)isoindoline-1,3-dione

(E)-2-(2-hydroxybenzylideneamino)isoindoline-1,3-dione (Hbid) was prepared by condensation of N-aminophthalimide and salicylaldehyde and characterized by elemental analysis, IR, 1H-NMR, and mass spectral studies. Mononuclear complexes [(phen)Cu

Studies in Antifertility Agents : Part XXXVI-Syntheses of N-(Substituted benzylidene)amino-phthalimides, -dihydroisoindoles and -1,2,3,4-tetrahydroisoquinolines

Syntheses and antifertility activity of a number of N-(substituted benzylidene)amino-phthalimides (3a-i), -dihydroisoindoles (4a-i) and -1,2,3,4-tetrahydroisoquinolines (5a-i) are reported.Some of these compounds prevent pregnancy when administered at 25 mg/kg/day in mice. 100percent abortifacient actvity has been shown by some of these compounds in rats at 20 mg/kg.