32387-02-3

Usage

Molecular weight

339.34 g/mol

Structure

A complex organic compound containing a methoxybenzylideneamino group attached to an isoindole-1,3(2H)-dione core.

Biological and pharmacological activities

Has potential anti-cancer and anti-inflammatory properties, has been shown to inhibit the growth of certain cancer cells, and reduce inflammation in experimental models.

Electronic and optical properties

Has interesting electronic and optical properties, making it a potential candidate for use in organic electronics.

Further research needed

More research is required to fully understand the potential applications of 2-[(2-methoxybenzylidene)amino]-1H-isoindole-1,3(2H)-dione.

Upstream product

• 1875-48-5 N-aminophthalamide 
• 135-02-4 ortho-anisaldehyde 

Downstream Products

• 71271-35-7 4-(2-methoxy-phenyl)-2H-phthalazin-1-one 
• 99755-87-0 3-Hydroxy-2-{[1-(2-methoxy-phenyl)-meth-(E)-ylidene]-amino}-3-m-tolyl-2,3-dihydro-isoindol-1-one 
• 57835-94-6 4-(1-naphthyl)phthalaz-1-one 

Relevant academic research and scientific papers

Action of Grignard Reagents and Amines on Some N-(Arylmethyleneamino)phthalimides

N-(Arylmethyleneamino)phthalimides (2a-c) carrying an o-substituent in the aryl group were prepared by the reaction of N-aminophthalimide with o-substituted benzaldehydes.The reaction of these compounds with Grignard reagents proceeded either by normal addition to one of the carbonyl groups to give 3a-c or by addition and cleavage to give 4-arylphthalaz-1-ones 5a-c.The steric effect exhibited by either the Grignard reagent or the N-arylmethylene compound was studied.The reaction of N-furfurylideneaminophthalimide (2d) with Grignard reagents was also investigated.N-( Arylmethyleneamino)phthalimides reacted with primary amines to give N,N'-dialkylphthalamides (7a and b) while the reaction with secondary amines gave (8a and b).

Studies in Antifertility Agents : Part XXXVI-Syntheses of N-(Substituted benzylidene)amino-phthalimides, -dihydroisoindoles and -1,2,3,4-tetrahydroisoquinolines

Syntheses and antifertility activity of a number of N-(substituted benzylidene)amino-phthalimides (3a-i), -dihydroisoindoles (4a-i) and -1,2,3,4-tetrahydroisoquinolines (5a-i) are reported.Some of these compounds prevent pregnancy when administered at 25 mg/kg/day in mice. 100percent abortifacient actvity has been shown by some of these compounds in rats at 20 mg/kg.