32387-96-5Relevant academic research and scientific papers
New quinoxalin-1,3,4-oxadiazole derivatives: Synthesis, characterization, in vitro biological evaluations, and molecular modeling studies
Mirzazadeh, Roghieh,Asgari, Mohammad S.,Barzegari, Ebrahim,Pedrood, Keyvan,Mohammadi-Khanaposhtani, Maryam,Sherafati, Maedeh,Larijani, Bagher,Rastegar, Hossein,Rahmani, Hojjat,Mahdavi, Mohammad,Taslimi, Parham,Eda M.,Gul?in, ?lhami
, (2021/05/19)
A new series of quinoxalin-1,3,4-oxadiazole (10a–l) derivatives was synthesized and evaluated against some metabolic enzymes including human carbonic anhydrase (hCA) isoenzymes I and II (carbonic anhydrases I and II), cholinesterase (acetylcholinesterase
HBTU-catalyzed simple and mild protocol for the synthesis of quinoxaline derivatives
Bhushan, B. Popatkar,Gangadhar, A. Meshram
, (2020/07/21)
HBTU-catalyzed, simple, mild, and effective protocol for the synthesis of quinoxalines has been established. The reaction between 1,2-diamines, benzil, and catalytic amount of HBTU in ethanol resulted into quinoxalines. Various aliphatic, aromatic and het
Triketone compound containing quinoxaline structure, and preparation method and application thereof
-
Paragraph 0101-0103, (2020/03/13)
The invention belongs to the technical field of medicine synthesis, and particularly relates to a triketone compound containing a quinoxaline structure, and a preparation method and an application thereof. The quinoxaline-containing triketone compound has a structure represented by general formula (I). The preparation method is mainly characterized in that a compound with a structure represented by formula (II) is contacted in the presence of an alkali and a solvent, and R1, R2, R3 and R4 in the formulas are respectively defined in the description. The quinoxaline-containing triketone compoundhas high herbicidal activity, and especially has an excellent effect of preventing and controlling broadleaf weeds and/or gramineous weeds, and the prevention and control effect is even better than that of some commercial herbicides sold in the market.
COMPOSITIONS AND METHODS OF MODULATING SHORT-CHAIN DEHYDROGENASE ACTIVITY
-
Paragraph 00480, (2018/08/26)
Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors de
A NOVEL QUINOXALINE COMPOUND FOR ULTRAVIOLET ABSORBERS
-
Paragraph 0087-0089; 0111-0113, (2017/10/21)
PURPOSE: A novel quinoxaline compound, isomer thereof, precursor drug thereof, or pharmaceutically acceptable salt thereof is provided to absorb UVA and UVB. CONSTITUTION: A quinoxaline compound is denoted by chemical formula 1. An UV absorber or pharmaceutical or cosmetic composition for antiaging contains the quinoxaline compound, isomer thereof, precursor drug thereof, or pharmaceutically acceptable salt, hydrate, or solvate thereof as an active ingredient.
Catalytic application of recyclable silica-supported bismuth(III) chloride in the benzo[N,N]-heterocyclic condensation
Aghapoor, Kioumars,Mohsenzadeh, Farshid,Shakeri, Atena,Darabi, Hossein Reza,Ghassemzadeh, Mitra,Neumüller, Bernhard
, p. 170 - 178 (2013/10/08)
Silica-supported bismuth(III) chloride (BiCl3/SiO2) has been successfully employed in the condensation of 1,2-dicarbonyls with a variety of arene-1,2-diamines bearing either electron withdrawing or donating functional groups. The catalyzed reaction proceeded smoothly under ambient temperature in methanol to give the corresponding quinoxaline and pyrido[2,3-b]pyrazine compounds in good to excellent yields. The catalyst exhibited remarkable reusable activity and higher catalytic performance than homogeneous BiCl3. A plausible mechanism for the catalytic action of BiCl3/SiO2 has been introduced. Moreover, the crystal structure of the prepared unsymmetrical benzo[N,N]-heterocycles has been determined by single crystal X-ray diffraction.
A recyclable solid acid catalyst sulfated titania for easy synthesis of quinoxaline and dipyridophenazine derivatives under microwave irradiation
Krishnakumar, Balu,Swaminathan, Meenakshisundaram
experimental part, p. 1261 - 1266 (2012/01/31)
TiO2SO42, prepared by solgel method has been used for the synthesis of quinoxaline and dipyridophenizine derivatives under microwave irradiation. High-resolution transmission electron microscope (HR-TEM) and atomic force m
Solvent free synthesis of quinoxalines, dipyridophenazines and chalcones under microwave irradiation with sulfated Degussa titania as a novel solid acid catalyst
Krishnakumar,Swaminathan
experimental part, p. 16 - 25 (2011/12/14)
Sulfated TiO2-P25 (Degussa titania) has been prepared by sol-gel method using H2SO4 and characterized by FT-IR, XRD, FE-SEM, EDS, HR-TEM, XPS, DRS and BET surface area measurements. Sulfate loading by H2SO4 increases the Lewis acidity of Degussa tiatania. This catalyst gives an excellent yield with less reaction time and is an inexpensive and easily recyclable solid acid catalyst for the synthesis of quinaxalines, dipyridophenazines and chalcones under microwave irradiation.
An efficient protocol for the green synthesis of quinoxaline and dipyridophenazine derivatives at room temperature using sulfated titania
Krishnakumar,Velmurugan,Jothivel,Swaminathan
experimental part, p. 997 - 1002 (2010/10/03)
Biologically active quinoxalines and dipyridophenazines were efficiently synthesized in excellent yield and less reaction time using inexpensive, easily recyclable sulfated titania (TiO2-SO42-). TiO2-SO42-
A recyclable and highly effective sulfated TiO2-P25 for the synthesis of quinoxaline and dipyridophenazine derivatives at room temperature
Krishnakumar,Swaminathan
experimental part, p. 2572 - 2577 (2010/11/18)
Sulfated TiO2-P25 has been prepared using H2SO 4 and used for the synthesis of quinoxaline and dipyridophenazine derivatives. Sulfate loading by H2SO4 increases the Lewis acidity of TiO2-P2
