32392-48-6

Upstream product

• 826-62-0 5-norbornene-2,3-dicarboxylic anhydride 
• 56-40-6 glycine 

Downstream Products

• 444338-55-0 4-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]-4-azatricyclo[5.2.1.0(2,6)]dec-8-ene-3,5-dione 
• 444185-25-5 4-{2-[4-(3-chlorophenyl)piperazin-1-yl]-2-oxoethyl}-4-azatricyclo[5.2.1.0(2,6)]dec-8-ene-3,5-dione 
• 1160211-91-5 2-{9-(4-nitrophenyl)-3,5-dioxo-4,9-diazatetracyclo[5.3.1.0^2-exo,6-exo.0^8-exo,12-exo]undec-4-yl}ethanoic acid 

Relevant academic research and scientific papers

MOLECULE, AND CADMIUM SENSOR AND METHOD THEREOF

The subject matter provides a device and a molecule and method thereof. The device comprising norbornene derived 8-hydroxyquinoline (N8HQ). In one embodiment the device comprises a strip having coating norbornene derived 8- hydroxyquinoline (N8HQ). In one embodiment, the device comprises polymer norbornene derived 8-hydroxyquinoline (PN8HQ). In another embodiment, the strip comprises coating for polymer norbornene derived 8-hydroxyquinoline (PN8HQ). According to a further aspect, the strip is a paper, wooden, plastic, metal, glass, china strip or any strip made of material that supports coating of norbornene derived 8-hydroxyquinoline(N8HQ) or its polymer and to enable detecting of cadmium. According to one aspect of the present subject matter the device being a polymer based device.

Synthesis and anticonvulsant properties of new acetamide derivatives of phthalimide, and its saturated cyclohexane and norbornene analogs

The synthesis and anticonvulsant properties of new piperazine or morpholine acetamides derived from 2-(1,3-dioxoisoindolin-2-yl)-, 2-(1,3-dioxo-3a,4,5,6,7, 7a-hexahydroisoindol-2-yl-) and (3,5-dioxo-4-azatricyclo[5.2.1.0 2,6]dec-8-en-4-yl)-acetic acid were described. Initial anticonvulsant screening was performed using maximal electroshock (MES) and subcutaneous pentylenetetrazole (scPTZ) seizures tests. The neurotoxicity was determined applying the minimal motor impairment rotarod test. The in vivo results revealed that numerous compounds were effective in the MES screen. The most active was 2-{2-[4-(4-fluorophenyl)piperazin-1-yl]-2-oxoethyl}isoindoline-1,3-dione (12) that revealed protection in the electrically induced seizures at a dose of 30 mg/kg and 100 mg/kg 0.5 h and 4 h after i.p. administration in mice respectively. This molecule given orally in rats at a dose of 30 mg/kg was more potent than reference anticonvulsant - phenytoin.