32407-68-4

Upstream product

• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 73663-61-3 5-(3,4-Dimethoxyphenyl)oxazole 
• 73663-56-6 (3,4-Dimethoxy-phenyl)-[5-(3,4-dimethoxy-phenyl)-oxazol-2-yl]-methanol 

Relevant academic research and scientific papers

Oxazoles in Organic Chemistry. 2. Application to the Synthesis of Benzylisoquinoline Alkaloids

A conceptually new route to the benzylisoquinoline alkaloids has been devised.The reaction of 2-lithiooxazoles with aromatic aldehydes to generate the thermodynamically favored 2-substituted oxazoles constitutes the key step in this process.A single-pot two carbon-carbon bond-joining reaction leading to an oxazoline suitable for further transformation to a phenethylamide is also described.