32407-75-3Relevant articles and documents
Aryne-Mediated Arylation of the 3-Benzazepine Scaffold: One-Pot Synthesis of 1-Aryl-3-methyl-2,3,4,5-tetrahydro-1 H -3-benzazepines
Singh, Kamal Nain,Singh, Paramjit,Sharma, Esha,Kaur, Manjot,Deol, Yadwinder Singh
, p. 3212 - 3220 (2015)
The coupling of β-amino carbanions derived from 3-benzA"azeA"pines with in situ generated arynes has been demonstrated as a convenient route for the direct synthesis of a variety of 1-aryl-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepines, including the biologically active drug molecule SCH 12679.
Rearrangement of 1-(α-Hydroxybenzyl)-1,2,3,4-tetrahydroisoquinolines to 1-Phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
McMahon, Robert M.,Thornber, Craig W.,Ruchirawat, Somsak
, p. 2163 - 2168 (2007/10/02)
When methoxy-substituted 1-(α-hydroxybenzyl)-1,2,3,4-tetrahydroisoquinolines are heated in formic acid they rearrange initially to give 5-phenyl-2,3-dihydro-1H-3-benzazepines which, on further heating in formic acid, are reduced to 1-phenyl-2,3,4,5-tetrah