32431-44-0

Basic information

• Product Name: Benzenamine, N-(2,2-diethoxyethyl)-3-methoxy-
• CAS NO: 32431-44-0
• Molecular Formula: C13H21NO3
• Molecular Weight: 239.315
• Mol File: 32431-44-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzenamine, N-(2,2-diethoxyethyl)-3-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, N-(2,2-diethoxyethyl)-3-methoxy-(32431-44-0)
• EPA Substance Registry System: Benzenamine, N-(2,2-diethoxyethyl)-3-methoxy-(32431-44-0)

Safety Data

• Hazardous Substances Data: 32431-44-0(Hazardous Substances Data)

Upstream product

• 536-90-3 m-Anisidine 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 

Downstream Products

• 99546-93-7 N-(2,2-diethoxyethyl)-N-(3-methoxyphenyl)-benzene-sulfonamide 
• 4837-90-5 4-methoxy-1H-indole 
• 3189-13-7 6-methoxylindole 
• 99532-46-4 1-(6-methoxy-1-(phenylsulfonyl)-1H-indol-3-yl)ethanone 
• 99532-52-2 1-(6-methoxy-1H-indol-3-yl)ethan-1-one 
• 56995-13-2 6-methoxy-1-(phenylsulfonyl)-1H-indole 
• 75934-38-2 N-(2,2-Diethoxy-ethyl)-2,2,2-trifluoro-N-(3-methoxy-phenyl)-acetamide 

Relevant articles and documents

SYNTHESIS OF INDOLES FROM N-(TRIFLUOROACETYL)-2-ANILINO ACETALS

N-(trifluoroacetyl)indoles (3) are produced in high yield from appropriately ring-substituted N-(trifluoroacetyl)-2-anilino acetals (2) in boiling trifluoroacetic acid containing excess trifluoroacetic anhydride.Mild saponification provides the free indoles nearly quantitatively.The scope of the reaction is discussed.The ring closure follows solvolytic substitution of a trifluoroacetoxy group for one of the ethoxy groups in 2.The method has been extended to cyclization of N-(trifluoroacetyl)-α-anilinoacetone in hot polyphosphoric acid followed by saponification to yield 3-methylindole.