32445-68-4

Upstream product

• 67-56-1 methanol 

Downstream Products

• 156043-74-2 4-[(2S,4S,5S)-4-Benzyloxy-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-1-(triphenyl-λ⁵-phosphanylidene)-butan-2-one 
• 156043-72-0 Toluene-4-sulfonic acid (2R,4S,5R)-4-benzyloxy-5-dimethoxymethyl-tetrahydro-furan-2-ylmethyl ester 
• 156043-66-2 (2R,3S,5R)-3-Benzyloxy-2-dimethoxymethyl-5-iodomethyl-tetrahydro-furan 
• 156043-67-3 (2R,3S)-3-Benzyloxy-1,1-dimethoxy-hex-5-en-2-ol 

Relevant academic research and scientific papers

Total synthesis of halichondrin B from common sugars: An F-ring intermediate from D-glucose and efficient construction of the C1 to C21 segment

An F-ring intermediate 7, with correct absolute configurations for the stereocenters at positions 17 and 20 of halichondrin B, is readily available from D-glucose. The practical utility of methoxybenzyl furanoside derivatives was demonstrated during incorporation of 7 into an acid-sensitive C1 to C21 segment.