324538-39-8

Upstream product

• 5398-36-7 2-aminothiazole-4-carboxylate 
• 1623-95-6 4-phenoxybenzoyl chloride 

Downstream Products

• 827039-01-0 2-[(4-tert-butyl-cyclohexyl)-(4-phenoxy-benzoyl)-amino]-thiazole-4-carboxylic acid ethyl ester 
• 827039-00-9 2-[(4-tert-butyl-cyclohexyl)-(4-phenoxy-benzoyl)-amino]-thiazole-4-carboxylic acid ethyl ester 
• 827038-99-3 2-[(4-methyl-cyclohexyl)-(4-phenoxy-benzoyl)-amino]-thiazole-4-carboxylic acid ethyl ester 
• 827038-98-2 2-[(4-methyl-cyclohexyl)-(4-phenoxy-benzoyl)-amino]-thiazole-4-carboxylic acid ethyl ester 
• 827038-95-9 2-[isopropyl-(4-phenoxy-benzoyl)-amino]-thiazole-4-carboxylic acid ethyl ester 
• 827038-94-8 2-[cyclohexyl-(4-phenoxy-benzoyl)-amino]-thiazole-4-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Aminothiazole inhibitors of HCV RNA polymerase

Aminothiazole-based inhibitors designed for HCV polymerase display low micromolar potencies in biochemical assays. These compounds show a stringent preference for a cyclohexyl hydrophobe at the 2-amino position. The composition of these compounds suggests that they may be interacting at a recently discovered allosteric site on the polymerase.