324541-81-3

Basic information

• Product Name: 4,8-Methano-1,3-dioxolo[4,5-d]oxepin-5-ol,hexahydro-2,2-dimethyl-,(3aS,4R,8R,8aR)-(9CI)
• Synonyms: 4,8-Methano-1,3-dioxolo[4,5-d]oxepin-5-ol,hexahydro-2,2-dimethyl-,(3aS,4R,8R,8aR)-(9CI)
• CAS NO: 324541-81-3
• Molecular Formula: C10H16O4
• Molecular Weight: 200.23
• Product Categories: CYCLOPENTANE
• Mol File: 324541-81-3.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4,8-Methano-1,3-dioxolo[4,5-d]oxepin-5-ol,hexahydro-2,2-dimethyl-,(3aS,4R,8R,8aR)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4,8-Methano-1,3-dioxolo[4,5-d]oxepin-5-ol,hexahydro-2,2-dimethyl-,(3aS,4R,8R,8aR)-(9CI)(324541-81-3)
• EPA Substance Registry System: 4,8-Methano-1,3-dioxolo[4,5-d]oxepin-5-ol,hexahydro-2,2-dimethyl-,(3aS,4R,8R,8aR)-(9CI)(324541-81-3)

Safety Data

• Hazardous Substances Data: 324541-81-3(Hazardous Substances Data)

Upstream product

• 59340-69-1 1-((3aS,4S,6R,6aR)-6-Hydroxymethyl-2,2-dimethyl-tetrahydro-cyclopenta[1,3]dioxol-4-yl)-ethane-1,2-diol 
• 112021-06-4 2α,3α-dihydroxy-di-O-isopropylidene-1β-hydroxymethyl-4β-(2-phenylstyryl)cyclopentane 
• 120707-15-5 (-)-(1R)-menthyl 5-exo,6-exo-(isopropylidenedioxy)-3-endo-(2-pyridinylsulphonyl)bicyclo<2.2.1>heptane-2-endo-carboxylate 
• 120521-51-9 (-)-(R_S)-menthyl 5-exo,6-exo-(isopropylidenedioxy)-3-endo-(2-pyridylsulphinyl)-bicyclo<2.2.1>heptane-2-carboxylate 
• 110522-48-0 (+)-(1R,S_S)-menthyl 3-endo-(2-pyridylsulphinyl)bicyclo-<2.2.1>hept-5-ene-2-endo-carboxylate 
• 110550-21-5 (-)-(1R)-menthyl 5-exo,6-exo-(isopropylidenedioxy)bicyclo-<2.2.1>hept-2-ene-2-carboxylate 
• 120424-44-4 (-)-(1R)-menthyl 5-exo,6-exo-(isopropylidenedioxy)bicyclo<2.2.1>heptane-2-α/β-carboxylate 
• 120521-54-2 (+)-(1S)-2-(dimethyl-t-butylsiloxy)-5-exo,6-exo-(isopropyl-idenedioxy)bicyclo<2.2.1>hept-2-ene 
• 120521-53-1 (-)-(1S)-5-exo,6-exo-(isopropylidenedioxy)bicyclo<2.2.1>heptan-2-one 
• 120424-46-6 (+)-(1R)-5-exo,6-exo-(isopropylidenedioxy)bicyclo<2.2.1>heptane-2α/β-carbaldehyde 
• 120424-45-5 (+)-(1R)-5-exo,6-exo-(isopropylidenedioxy)bicyclo<2.2.1>heptan-2α/β-ylmethanol 
• 120424-49-9 (+)-(1S,4R)-methyl-4α-dimethoxymethyl-2α,3α-(isopropylidenedioxy)cyclopentane-1α-carboxylate 
• 120424-47-7 (-)-(1R)-(2E/Z)-(dimethyl-t-butylsiloxyethylidene)-5-exo,6-exo-(isopropylidenedioxy)bicyclo<2.2.1>heptane 
• 120424-50-2 (-)-(1R,4R)-4α-dimethoxymethyl-2β,3β-(isopropylidenedioxy)cyclopentylmethanol 

Relevant articles and documents

Lipase-mediated preparation of a functionalized bicyclo[3.2.1]octenone and a practical utilization

Both enantiomers of a functionalized bicyclo[3.2.1]octane molecule potentially useful as a versatile chiral building block have been prepared in enantiomerically pure forms from norbomadiene by employing lipase-mediated kinetic resolution. By transforming both enantiomers enantioconvergently into the same chiral lactone serving as the key intermediate for the synthesis of the naturally occurring carbocyclic nucleoside (-)-aristeromycin, the absolute configuration of the resolved products has been established and at the same time their synthetic potential has been demonstrated.

Titanium Tetrachloride-Mediated Diels-Alder Reactions of Cyclopentadiene with Di-l-menthyl Methylenemalonate and Its Acetoxy Derivative as New Chiral Dienophiles for Asymmetric Induction

Asymmetric synthesis of -2,3-dihydroxy-4-hydroxymethylcyclopent-1ylmalonate (its racemic form is already known as a versatile building block for carbocyclic C-nucleosides) was achieved by Diels-Alder reaction of cyclopentadiene with di-l-ment