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Uridine, 2',3'-O-(1-methylethylidene)-3-(phenylmethyl)-, also known as 2',3'-O-isopropylidene-3-benzyluridine, is a chemical compound derived from uridine, a nucleoside consisting of the base uracil attached to a ribose sugar. This specific derivative features a 1-methylethylidene (isopropylidene) group protecting the 2' and 3' hydroxyl groups of the ribose sugar, as well as a phenylmethyl (benzyl) group attached to the 3-position of the uridine molecule. This modification is often used in organic synthesis and biochemistry to protect certain functional groups during chemical reactions, and it can also be employed to study the interactions of uridine with enzymes and other biomolecules. The compound is typically used in research settings to investigate the structure and function of nucleic acids and their derivatives.

32464-90-7

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32464-90-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 32464-90-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,4,6 and 4 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 32464-90:
(7*3)+(6*2)+(5*4)+(4*6)+(3*4)+(2*9)+(1*0)=107
107 % 10 = 7
So 32464-90-7 is a valid CAS Registry Number.

32464-90-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name N3-benzyl-2',3'-O-isopropylideneuridine

1.2 Other means of identification

Product number -
Other names N(3)-benzyl-2,3-O-isopropylideneuridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:32464-90-7 SDS

32464-90-7Relevant academic research and scientific papers

Synthesis and central nervous system depressant effects of N3- substituted 2',3'-O-isopropylideneuridines

Yao, Che Shun,Kimura, Toshiyuki,Watanabe, Kazuhito,Kondo, Shigemi,Ho, Ing Kang,Yamamoto, Ikuo

, p. 1802 - 1804 (1999)

N3-Substituted derivatives of 2',3'-O-isopropylideneuridine (1) were synthesized and their pharmacological effects on the central nervous system (CNS) examined using mice. Methyl (2), ethyl (3), propyl (4), butyl (5), allyl (6), benzyl (7), o-, m-,p-xylyls (8, 9, 10), and α-phenylethyl (11) derivatives of 1 were administered to mice by intracerebroventricular (i.c.v.) injection for evaluating hypnotic activity, pentobarbital-induced sleep prolongation, and spontaneous activity as indices. Only 3 possessed hypnotic activity by i.c.v. injection at the dose of 2.0 μmol/mouse. Compounds 3, 4, and 10 significantly showed synergism with a barbiturate, indicating that the derivatives have some CNS depressant effects. Moreover, 3 and 4 caused decrease in the spontaneous activity of mice, even at low doses. The present study indicated that substitution by ethyl, propyl, and p-xylyl groups at the N3-position of 2',3'-O-isopropylideneuridine imparted the CNS depressant effects.

Palladium catalysed tandem cyclisation-anion capture. Part 6: Synthesis of sugar, nucleoside, purine, benzodiazepinone and β-lactam analogues via capture of in situ generated vinylstannanes

Casaschi, Adele,Grigg, Ronald,Sansano, José M.

, p. 7553 - 7560 (2007/10/03)

The regioselective palladium catalysed hydrostannylation of alkynes bearing a β-heteroatom affords mainly α-vinyltin(IV) compounds that are used as terminating species in palladium catalysed cyclisation-anion capture processes. The pharmacophore attached

General Method for the Preparation of N3- and O4-Substituted Uridine Derivatives by Phase-Transfer Reactions

Sekine, Mitsuo

, p. 2321 - 2326 (2007/10/02)

A general method for regioselective introduction of a variety of protecting groups into the uracil residue of 1 has been developed by use of the phase-transfer reaction.Under such conditions, acyl groups such as benzoyl, p-toluyl, p-anisoyl, (2,2,2-trichl

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