324763-45-3

Basic information

• Product Name: (3S,5S)-5-{(1R,3S)-1-hydroxy-3-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-methylpentyl}-3-(1-methylethyl)dihydrofuran-2(3H)-one
• CAS NO: 324763-45-3
• Molecular Formula: C₂₅H₄₀O₆
• Molecular Weight: 436.5815
• Mol File: 324763-45-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 575.1°C at 760 mmHg
• Flash Point: 185.6°C
• Density: 1.066g/cm³
• Vapor Pressure: 4.57E-14mmHg at 25°C
• Refractive Index: 1.504
• CAS DataBase Reference: (3S,5S)-5-{(1R,3S)-1-hydroxy-3-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-methylpentyl}-3-(1-methylethyl)dihydrofuran-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,5S)-5-{(1R,3S)-1-hydroxy-3-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-methylpentyl}-3-(1-methylethyl)dihydrofuran-2(3H)-one(324763-45-3)
• EPA Substance Registry System: (3S,5S)-5-{(1R,3S)-1-hydroxy-3-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-methylpentyl}-3-(1-methylethyl)dihydrofuran-2(3H)-one(324763-45-3)

Safety Data

• Hazardous Substances Data: 324763-45-3(Hazardous Substances Data)

Upstream product

• 324763-38-4 N-(2-hydroxy-1-methyl-2-phenyl-ethyl)-2-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-3,N-dimethyl-butyramide 
• 324763-37-3 N-(2-hydroxy-1-methyl-2-phenyl-ethyl)-3-[4-methoxy-3-(3-methoxy-propoxy)-phenyl]-N-methyl-propionamide 
• 324763-41-9 (2S,3S,5R,7S,9S)-7-Bromomethyl-9-isopropyl-3,4-dimethyl-2-phenyl-1,6-dioxa-4-aza-spiro[4.4]nonane 
• 172900-71-9 (R)-3-[4-methoxy-3-(3-methoxypropoxy)phenyl]-2-(1-methylethyl)propanoic acid 
• 172900-70-8 (R)-2-[4-methoxy-3-(3-methoxypropoxy)benzyl]-3-methylbutanol 
• 324763-42-0 ((2S,3S,5R,7S,9S)-9-Isopropyl-3,4-dimethyl-2-phenyl-1,6-dioxa-4-aza-spiro[4.4]non-7-yl)-methanol 
• 324763-39-5 (R)-2-[4-methoxy-3-(3-methoxypropoxyl)]phenylmethyl-3-methyl-1-chlorobutane 
• 324763-40-8 (S)-2-Isopropyl-pent-4-enoic acid ((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide 
• 324763-36-2 (E)-3-[4-Methoxy-3-(3-methoxy-propoxy)-phenyl]-acrylic acid 
• 325740-58-7 (2S,4S)-4-Isopropyl-5-oxo-tetrahydro-furan-2-carboxylic acid benzyl ester 
• 172900-75-3 4-methoxy-3-(3-methoxypropoxy)benzaldehyde 
• 325740-60-1 tetrahydro-4-isopropyl-5-oxofuran-2-carbonyl chloride 
• 325740-59-8 tetrahydro-4-isopropyl-5-oxofuran-2-carboxylic acid 
• 325740-56-5 (S)-4-Isopropyl-5-oxo-tetrahydro-furan-2-carbonyl chloride 

Downstream Products

• 324763-46-4 (3S,5S)-5-{(1S,3S)-1-azido-3-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methylpentyl}-dihydro-3-(1-methylethyl)furan-2(3H)-one 
• 173334-57-1 (2S,4S,5S,7S)-5-Amino-4-hydroxy-2-isopropyl-7-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-8-methyl-nonanoic acid (2-carbamoyl-2-methyl-propyl)-amide 
• 324763-47-5 (2S,4S,5S,7S)-N-(3-amino-2,2-dimethyl-3-oxopropyl)-5-azido-4-hydroxy-2-isopropyl-7-(4-methoxy-3-(methoxypropoxy)benzyl)-8-methylnonanamide 
• 387353-75-5 4-Bromo-benzenesulfonic acid (1R,3S)-1-((2S,4S)-4-isopropyl-5-oxo-tetrahydro-furan-2-yl)-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl ester 

Relevant articles and documents

A convergent synthesis of the renin inhibitor CGP60536B

Pseudoephedrine serves as a dual purpose chiral auxiliary and protecting group in the synthesis of the novel orally active renin inhibitor CGP60536B. (C) 2000 Elsevier Science Ltd.