3249-28-3

Usage

Uses

Used in Flavor and Fragrance Industry:
Hexa-2,4-dienedial is used as an intermediate in the synthesis of (2E,4E,6Z)-2,4,6-nonatrienal (N649575), a natural aroma compound that imparts desirable flavors and fragrances to a variety of foods, such as oats and black tea. Its role in the synthesis process is crucial for creating complex and appealing sensory profiles in these food products.
Used in Chemical Synthesis:
Hexa-2,4-dienedial is also utilized as a versatile intermediate in the chemical synthesis of various compounds, owing to its reactive diene and aldehyde groups. This makes it a valuable building block for the development of new molecules with potential applications in various industries, such as pharmaceuticals, materials science, and agrochemicals.

InChI:InChI=1/C6H6O2/c7-5-3-1-2-4-6-8/h1-6H

Upstream product

• 94582-88-4 1,1,4,6,6-pentamethoxy-hex-2-ene 
• 71-43-2 benzene 
• 108-95-2 phenol 

Relevant academic research and scientific papers

Comprehensive NO-dependent study of the products of the oxidation of atmospherically relevant aromatic compounds

A comprehensive product study, performed via the turbulent flow chemical ionization mass spectrometry (TF-CIMS) technique, of the primary OH-initiated oxidation of many of the atmospherically abundant aromatic compounds was performed. The bicyclic peroxy radical intermediate, a key proposed intermediate species in the Master Chemical Mechanism (MCM) for the atmospheric oxidation of aromatics, was detected in all cases, as were stable bicyclic species. The NO product yield dependences suggest a potential role for bicyclic peroxy radical + HO2 reactions at high HO2/NO ratios, which are postulated to be a possible source of the inconsistencies between previous environmental chamber results and predictions from the MCM for ozone production and OH reactivity. The TF-CIMS product yield results are also compared to previous environment chamber results and to the latest MCM parametrization.

Determination of oxygen sources for oxidation of benzene on TiO2 photocatalysts in aqueous solutions containing molecular oxygen

Photocatalytic oxidation of benzene to CO2 was studied in aqueous solutions using different kinds of TiO2 powders, and isotopic oxygen tracers (H218O and 18O2) were used to investigate the oxidation process. Phenol was produced as a main intermediate in solution. When anatase powders, which showed high activity for oxidation of benzene, were used, 70-90% of oxygen introduced into phenol was from water. On the other hand, when rutile powders were used, only 20-40% of the oxygen was from water. The rest was from molecular oxygen in both cases. The rate of phenol production by using molecular oxygen was nearly the same between anatase and rutile powders. Hence, the high activity of anatase powders for oxidation of benzene to CO2 is attributed to their high activity for oxidation of benzene to phenol, which is considered to be the rate-determining step, using water as the oxygen source. The processes using water and molecular oxygen as the oxygen sources are ascribed, respectively, to oxygen transfer and hole transfer processes in the initial step of benzene oxidation.

Direct observation by 1H NMR of 4,5-benzoxepin-2,3-oxide and its surprisingly rapid ring-opening rearrangement to 1H-2-benzopyran-1- carboxaldehyde

The first unambiguous observation of an oxepin-2,3-oxide is reported. Between 5 and 10°C it rearranges rapidly to its isomer 1H-2-benzopyran-1- carboxaldehyde. In contrast, 2,3-oxides of monocyclic oxepins rearrange to stable, ring-opened dialdehydes or d

IR and UV spectra of ozonized phenol and guaiacol

The UV and IR spectra of products formed at various stages of the ozonization of phenol and guaiacol in distilled water and the kinetics of ozone reactions with phenol and guaiacol were studied. The oxidation of phenol with ozone involved successive stages of the formation of acids and aldehyde acids with two and one C=C bonds and the stage of the formation of glyoxalic acid. The rates of these reactions were commensurate. The oxidation of the guaiacol aromatic ring by ozone occurred at a much higher rate than the oxidation of phenol. The end products of the ozonolysis of phenol were formic and oxalic acids. With guaiacol, esters of these acids were also formed. The results of the spectral study of the ozonolysis of phenol and guaiacol were in agreement with the conclusions drawn based on kinetic data.