325147-50-0Relevant articles and documents
Direct Access to N-tert-Butanesulfinyl Imines from Aryl Iodides, Alkenyl Alcohols, and N-tert-Butanesulfinamide
Ikhlef, Sofiane,Behloul, Cherif,Lahosa, Alejandro,Foubelo, Francisco,Yus, Miguel
, p. 2609 - 2614 (2018/05/03)
The reaction of aryl iodides, N-tert-butanesulfinamide, and allyl or homoallyl alcohol in the presence of a catalytic amount of Pd(OAc)2, NaHCO3 as a base, and TBAB leads to the formation of N-tert-butanesulfinyl imines in moderate yields. In this one-pot process, a sequential Heck-type arylation of the alkenol, isomerization of the double bond, and imine formation take place.
Unsymmetrical biaryls by palladium-catalyzed coupling of aryl halides with internal reduction
Satyanarayana, Gedu,Maier, Martin E.
scheme or table, p. 5543 - 5552 (2009/05/11)
Aryl bromides containing a (1,4,5,6-tetrahydro-6-oxopyridin-3-yl)methyl substituent can be coupled with aryl halides yielding unsummetrical biaryls. In the course of this process, the cyclic enamide is oxidized to the 2(1H)-pyridinone. The reaction procee
Synthesis of 1,5-methano-3-benzazocines by intramolecular Buchwald-Hartwig arylation of 2-piperidinones
Satyanarayana, Gedu,Maier, Martin E.
, p. 356 - 363 (2008/04/01)
A conceptually novel route to 1,5-methano-3-benzazocines based on an intramolecular Buchwald-Hartwig arylation was developed. The reaction required the use of the zinc enolate of the piperidinone substrates. These substrates, piperidin-2-ones with a 2-bro
