325153-22-8

Basic information

• Product Name: 5-[(DIMETHYLAMINO)METHYLENE]-3-PHENYL-2-THIOXOTETRAHYDRO-4H-IMIDAZOL-4-ONE
• Synonyms: 5-[(DIMETHYLAMINO)METHYLENE]-3-PHENYL-2-THIOXOTETRAHYDRO-4H-IMIDAZOL-4-ONE;(5Z)-5-[(dimethylamino)methylidene]-3-phenyl-2-sulfanylideneimidazolidin-4-one
• CAS NO: 325153-22-8
• Molecular Formula: C₁₂H₁₃N₃OS
• Molecular Weight: 247.32
• Mol File: 325153-22-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-[(DIMETHYLAMINO)METHYLENE]-3-PHENYL-2-THIOXOTETRAHYDRO-4H-IMIDAZOL-4-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[(DIMETHYLAMINO)METHYLENE]-3-PHENYL-2-THIOXOTETRAHYDRO-4H-IMIDAZOL-4-ONE(325153-22-8)
• EPA Substance Registry System: 5-[(DIMETHYLAMINO)METHYLENE]-3-PHENYL-2-THIOXOTETRAHYDRO-4H-IMIDAZOL-4-ONE(325153-22-8)

Safety Data

• Hazardous Substances Data: 325153-22-8(Hazardous Substances Data)

Upstream product

• 2010-15-3 3-phenyl-2-thioxoimidazolidin-4-one 
• 1188-33-6 N,N-dimethylformamide diethyl diacetal 
• 103-72-0 phenyl isothiocyanate 

Downstream Products

• 1158718-86-5 ethyl (2E,3Z).4-(dimethylamino)-2-(5-oxo-1-phenyl-2-thioxoimidazolidin-4-ylidene)but-3-enoate(5-oxo-1-phenyl-2-thioxoimidazolidin-4-ylidene)butanediooate 
• 1158718-80-9 dimethyl (2E,3E)-2-[(dimethylamino)methylene]-3-(5-oxo-1-phenyl-2-thioxoimidazolidin-4-ylidene)butanedioate 
• 1158718-82-1 ethyl (2E,3E)-2-[(dimethylamino)methylene]-4,4,4-trifluoro-3-(5-oxo-1-phenyl-2-thioxoimidazolidin-4-ylidene)butanoate 
• 681014-88-0 5-[(Z)-(2-methyl-1H-indol-3-yl)methylidene]-3-phenyl-2-thioxoimidazolidin-4-one 

Relevant articles and documents

A practical and eco-friendly synthesis of stereocontrolled alkylaminomethylidene derivatives of 2-thiohydantoins by dimethylamine substitution

3-Alkyl-5-dimethyaminomethylidene-2-thioxo-imidazolidin-4-ones 3(a-c) available in two steps from methyl glycinate hydrochloride, represent a useful synthetic tool for efficient and mild solventless preparations of new alkylaminomethylidene derivatives of 2-thiohydantoins 8(a-e), 10(a-c) and 12(a-d) by stereocontrolled transamination reactions under microwave irradiations. The 1H, 13C NMR spectrum and the (5Z)-conformation of some representatives products are also discussed.