32541-62-1

Basic information

• Product Name: Benzoyl chloride, 3,5-dichloro-2,6-dimethoxy-
• CAS NO: 32541-62-1
• Molecular Formula: C9H7Cl3O3
• Molecular Weight: 269.512
• Mol File: 32541-62-1.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Benzoyl chloride, 3,5-dichloro-2,6-dimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoyl chloride, 3,5-dichloro-2,6-dimethoxy-(32541-62-1)
• EPA Substance Registry System: Benzoyl chloride, 3,5-dichloro-2,6-dimethoxy-(32541-62-1)

Safety Data

• Hazardous Substances Data: 32541-62-1(Hazardous Substances Data)

Upstream product

• 131335-43-8 methyl 3,5-dichloro-2,6-dihydroxybenzoate 
• 90793-91-2 methyl 3,5-dichloro-2,6-dimethoxybenzoate 
• 2150-45-0 methyl 2,6-dihydroxybenzoate 
• 73219-91-7 2,6-dimethoxy-3,5-dichlorobenzoic acid 
• 1466-76-8 2-6-dimethoxybenzoic acid 

Downstream Products

• 102805-62-9 3,5-Dichloro-N-(2-dimethylamino-butyl)-2,6-dimethoxy-benzamide 
• 102805-63-0 3,5-Dichloro-N-(2-diethylamino-propyl)-2,6-dimethoxy-benzamide 
• 102805-59-4 3,5-dichloro-2,6-dimethoxy-N-(2-dimethylaminoethyl)benzamide 
• 84225-95-6 raclopride 
• 113310-88-6 (S)-(-)-3,5-dichloro-N-((1-ethyl-2-pyrrolidinyl)methyl)-2,6-dihydroxybenzamide hydrobromide 
• 130880-24-9 3,5-Dichloro-N-[1-(4-chloro-benzyl)-piperidin-4-yl]-2-hydroxy-6-methoxy-benzamide 
• 130880-25-0 N-(1-Allyl-piperidin-4-yl)-3,5-dichloro-2-hydroxy-6-methoxy-benzamide 
• 130880-26-1 3,5-dichloro-6-methoxy-N-(1-methyl-4-piperidinyl)salicylamide 
• 132020-44-1 (+)-R-3,5-dichloro-N-{[1-(4-fluorobenzyl)-2-pyrrolidinyl]methyl}-6-methoxysalicylamide 
• 102805-78-7 3,5-Dichloro-N-(2-diethylamino-butyl)-2-hydroxy-6-methoxy-benzamide; hydrochloride 
• 102805-79-8 3,5-Dichloro-N-(2-dimethylamino-butyl)-2-hydroxy-6-methoxy-benzamide; hydrochloride 
• 102805-77-6 3,5-Dichloro-N-(2-diethylamino-ethyl)-2-hydroxy-6-methoxy-benzamide; hydrochloride 
• 102805-65-2 3,5-dichloro-2-hydroxy-6-methoxy-N-(2-dimethylaminoethyl)benzamide 
• 145351-55-9 (S)-5-<(3,5-dichloro-2-hydroxy-6-methoxybenzamido)methyl>-1-ethyl-2-pyrrolidone 

Relevant articles and documents

Synthesis and biological activities of new halophenols

A series of new halophenols were synthesized, and their structures were established on the basis of 1H, 13C NMR and mass spectral data. All of the prepared compounds were screened for their in vitro protein tyrosine kinase (PTK) and vascular smooth muscle cell (VSMC) proliferation inhibitory activity. Twelve halophenols showed significant PTK inhibitory activity, most of them exhibited stronger activities than that of genistein, a positive reference compound. Several halophenols also displayed moderate VSMC proliferation inhibitory activity, compound 8c showed higher activity than that of tetrandrine, a positive reference compound. The preliminary structure-activity relationships of these compounds were investigated and discussed. The results provided a foundation for the action mechanism study and further structure optimization of the halophenols.

A general method for the synthesis of raclopride, FLB 457 and epidepride and corresponding desmethyl-precursors

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Synthesis of Chiral 5-Substituted 2-Pyrrolidones, Metabolites of the Antipsychotic Benzamides Remoxipride and Raclopride

Three of the major human metabolites of remoxipride (1) and raclopride (6) have been synthesized in optically active form.Starting from L-pyroglutamic acid, the two pyrrolidones (+)-(5S)-5-(aminomethyl)-2-pyrrolidone (10) and (+)-(5S)-5-(aminomethyl)-1-et