325744-79-4Relevant academic research and scientific papers
Stereoselective total syntheses of (±)-arthrinone and related natural compounds
Uchiyama,Kimura,Ohta
, p. 10013 - 10017 (2000)
The first total syntheses of (±)-arthrinone, (±)-1-dehydroxyarthrinone, and (±)-3a,9a-deoxy-3a-hydroxyl-dehydroxyarthrinone, antifungal metabolites from the coprophilous fungus Cercophora sordarioides, were accomplished in a stereoselective manner. The ring systems of these metabolites, which were rare among natural products, were efficiently and diastereoselectively assembled using the [2,3]Wittig rearrangement and Diels-Alder reaction as the key steps. (C) 2000 Elsevier Science Ltd.
