325970-71-6 Usage
Uses
Used in Pharmaceutical Industry:
Glycine, N-(3,5-dibroMo-4-Methylphenyl)-, 2-[(2-hydroxy-5-nitrophenyl)Methylene]hydrazide is used as a DNA ligase inhibitor for the identification and validation of human DNA ligase inhibitors using computer-aided drug design. Its ability to selectively target cancerous cells and enhance the effectiveness of DNA-damaging agents makes it a promising candidate for the development of novel anticancer therapies.
Used in Research Applications:
In the field of molecular biology and cancer research, Glycine, N-(3,5-dibroMo-4-Methylphenyl)-, 2-[(2-hydroxy-5-nitrophenyl)Methylene]hydrazide serves as a valuable tool for studying the role of DNA ligases in DNA repair mechanisms and their implications in cancer progression. Its selectivity for cancer cells and induction of apoptosis provides insights into potential therapeutic targets and strategies for cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 325970-71-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,2,5,9,7 and 0 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 325970-71:
(8*3)+(7*2)+(6*5)+(5*9)+(4*7)+(3*0)+(2*7)+(1*1)=156
156 % 10 = 6
So 325970-71-6 is a valid CAS Registry Number.
325970-71-6Relevant academic research and scientific papers
TARGETING ABNORMAL DNA REPAIR IN THERAPY-RESISTANT BREAST AND PANCREATIC CANCERS
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, (2016/03/14)
In one embodiment, the invention provides a method of treating a subject suffering from a breast cancer tumor which is non-responsive or intrinsically resistant to anti-estrogen therapy comprising administering a therapeutically effective amount of an inh
