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(R)-2-{(2E,7E)-(5S,6R)-5-[(S)-2-(3-tert-Butoxycarbonylamino-propionylamino)-4-methyl-pentanoylamino]-6-methyl-8-phenyl-octa-2,7-dienoylamino}-3-(4-methoxy-phenyl)-propionic acid 2-trimethylsilanyl-ethyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

326473-67-0

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326473-67-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 326473-67-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,2,6,4,7 and 3 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 326473-67:
(8*3)+(7*2)+(6*6)+(5*4)+(4*7)+(3*3)+(2*6)+(1*7)=150
150 % 10 = 0
So 326473-67-0 is a valid CAS Registry Number.

326473-67-0Downstream Products

326473-67-0Relevant academic research and scientific papers

Synthesis of amide analogs of arenastatin A

Murakami, Nobutoshi,Wang, Weiqi,Ohyabu, Naoki,Ito, Takeshi,Tamura, Satoru,Aoki, Shunji,Kobayashi, Motomasa,Kitagawa, Isao

, p. 9121 - 9128 (2007/10/03)

In order to probe the metabolism of arenastatin A, a potent cytotoxic depsipeptide from the marine sponge Dysidea arenaria, we synthesized three analogs in which the ester linkages were replaced by amide bonds. Triamide analog-II and tetraamide analog, both of which contained a 15,20-amide linkage, showed stability in serum. However, arenastatin A and triamide analog-I, which both contained a 15,20-ester moiety, were readily metabolized in serum. Among the three amide analogs, only triamide analog-II exhibited potent cytotoxic activity against KB cells. (C) 2000 Elsevier Science Ltd.

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