32683-73-1Relevant academic research and scientific papers
Discovery and kinetic evaluation of 6-substituted 4-benzylthio-1,3,5- triazin-2(1H)-ones as inhibitors of cathepsin B
Sosi?, Izidor,Mirkovi?, Bojana,Turk, Samo,?tefane, Bogdan,Kos, Janko,Gobec, Stanislav
experimental part, p. 4648 - 4656 (2011/11/04)
Cathepsin B is a lysosomal cysteine protease that has various physiological and pathophysiological functions. We present here the discovery of 6-substituted 4-benzylthio-1,3,5-triazin-2(1H)-ones as inhibitors of cathepsin B, starting from screening of a l
The synthesis of novel 2,4,6-trisubstituted 1,3,5-triazines: A search for potential murf enzyme inhibitors
Sosic, Izidor,Stefane, Bogdan,Kovac, Andreja,Turk, Samo,Blanot, Didier,Gobec, Stanislav
experimental part, p. 91 - 115 (2010/05/19)
A series of new 2,4,6-trisubstituted 1,3,5-triazines, possessing a variety of substituents (-OH, -SH, -OMe, -Cl, -HNR, -SR and amino acid moieties), were synthesized and evaluated for the inhibition of the bacterial peptidoglycan biosynthesis enzyme MurF.
