326853-52-5

Upstream product

• 64308-75-4 (4S,5S)-(-)-5-Ethyl-2,2-dimethyl-4-(tosyloxymethyl)-1,3-dioxolan 
• 326866-10-8 (2S,3S)-2,3-dihydroxy-1-tosyloxypentane 
• 62-23-7 4-nitro-benzoic acid 
• 326853-58-1 Methanesulfonic acid (1R,6S,7S)-1-[(R)-2-benzyloxy-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-6-(tert-butyl-dimethyl-silanyloxy)-7-methoxymethoxy-non-3-ynyl ester 
• 326853-49-0 4-Nitro-benzoic acid (R)-1-[(2S,7R)-7-((R)-1-acetoxy-2-benzyloxy-ethyl)-2,3,6,7-tetrahydro-oxepin-2-yl]-propyl ester 
• 326853-65-0 (4S,5S)-4-Benzyloxymethyl-5-ethyl-2,2-dimethyl-[1,3]dioxolane 
• 111900-48-2 (2S,3S)-1,2-epoxy-3-hydroxypentane 
• 64273-32-1 (4S,5S)-4-ethyl-5-hydroxymethyl-1,3-dioxolane 

Relevant academic research and scientific papers

Formal synthesis of (+)-isolaurepinnacin

The stereoselective formal synthesis of (+)-isolaurepinnacin is described. The required key oxepene skeleton possessing cis-oriented alkyl substituents at the α,ω-positions was stereoselectively constructed via the cyclization of the corresponding hydroxy epoxide promoted by the (Bu3Sn)2O/Zn(OTf)2 system.