326894-84-2

Usage

Uses

Used in Cancer Treatment Research:
Pelitinib is used as a potential cancer treatment agent for targeting tumor cells that overexpress EGFR. It is particularly being investigated for its efficacy against head and neck cancer and non-small cell lung tumors.
Used in Research Applications:
Pelitinib is used as a research tool to study the role of EGFR in cancer cell growth and proliferation. It helps in understanding the mechanisms of EGFR inhibition and its impact on cancer cell signaling pathways.

Upstream product

• 99083-25-7 4-bromocrotonyl chloride 
• 124-40-3 dimethyl amine 
• 361162-95-0 6-amino-4-(3-chloro-4-fluoro-phenylamino)-7-ethoxy-quinoline-3-carbonitrile 
• 621-33-0 m-phenetidine 
• 492456-51-6 (E)-2-Cyano-3-(3-ethoxy-4-nitro-phenylamino)-acrylic acid ethyl ester 
• 361162-92-7 2-acetylamino-4-ethoxy-5-nitrobenzoic acid 
• 214476-08-1 7-Ethoxy-4-hydroxy-6-nitro-quinoline-3-carbonitrile 
• 214476-09-2 4-Chloro-7-ethoxy-6-nitro-quinoline-3-carbonitrile 
• 909513-02-6 (E)-2-Cyano-3-(3-ethoxy-phenylamino)-acrylic acid ethyl ester 
• 361162-91-6 5-ethoxy-2-methyl-4-nitroacetanilide 
• 214476-07-0 7-ethoxy-4-hydroxyquinoline-3-carbonitrile 
• 361162-90-5 5-methoxy-2-methyl-4-nitroacetanilide 
• 116435-75-7 3-(ethyloxy)-4-nitroaniline 
• 106579-00-4 5-methoxy-2-methyl-4-nitroaniline 

Relevant academic research and scientific papers

USE OF CYANOQUINOLINES FOR TREATING OR INHIBITING COLONIC POLYPS

This invention provides a method of treating or inhibiting colonic polyps which comprises providing a compound of formula (1); wherein R1, R2, R3, R4, X, Y, and n are defined hereinbefore, or a pharmaceutically acceptable salt thereof.

Synthesis and structure-activity relationships of 6,7-disubstituted 4-anilinoquinoline-3-carbonitriles. The design of an orally active, irreversible inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) and the human epi

A series of of 6,7-disubstituted-4-anilinoquinoline-3-carbonitrile derivatives that function as irreversible inhibitors of EGFR and HER-2 kinases have been prepared. These inhibitors have, at the 6-position, butynamide, crotonamide, and methacrylamide Mic

Method of treating or inhibiting colonic polyps

This invention provides a method of treating or inhibiting colonic polyps which comprises providing a compound of formula 1 wherein:R1, R2, R3, R4, X, Y, and n are as defined hereinbefore, or a pharmaceutically acceptable salt thereof.