361162-90-5

Basic information

• Product Name: 2-AcetaMido-4-Methoxy-5-nitrotoluene
• Synonyms: 2-AcetaMido-4-Methoxy-5-nitrotoluene;N-(5-methoxy-2-methyl-4-nitrophenyl)Acetamide
• CAS NO: 361162-90-5
• Molecular Formula: C₁₀H₁₂N₂O₄
• Molecular Weight: 224.21328
• Mol File: 361162-90-5.mol

Chemical Properties

• Melting Point: 139 °C
• Boiling Point: 432.4±45.0 °C(Predicted)
• Appearance: /
• Density: 1.283±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 13.46±0.70(Predicted)
• CAS DataBase Reference: 2-AcetaMido-4-Methoxy-5-nitrotoluene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AcetaMido-4-Methoxy-5-nitrotoluene(361162-90-5)
• EPA Substance Registry System: 2-AcetaMido-4-Methoxy-5-nitrotoluene(361162-90-5)

Safety Data

• Hazardous Substances Data: 361162-90-5(Hazardous Substances Data)

Usage

Chemical compound

2-Acetamido-4-methoxy-5-nitrotoluene

Main use

Intermediate in the synthesis of pharmaceuticals and dyes

Physical state

Yellow crystalline solid

Melting point

118-119°C

Sensitivity

Sensitive to light, moisture, and air

Storage recommendation

Store in a cool, dry place

Toxicity

Not highly toxic to humans, but may cause irritation to eyes, skin, and respiratory system

Handling recommendation

Typically used in laboratory settings by trained professionals following strict safety guidelines.

Upstream product

• 106579-00-4 5-methoxy-2-methyl-4-nitroaniline 
• 108-24-7 acetic anhydride 
• 50868-72-9 5-methoxy-o-toluidine 
• 50868-75-2 5’-methoxy-2’-methylacetanilide 

Downstream Products

• 749223-61-8 6-methoxy-1H-indazol-5-amine 
• 152626-75-0 6-methoxy-5-nitro-1H-indazole 
• 361162-91-6 5-ethoxy-2-methyl-4-nitroacetanilide 
• 859944-07-3 benzoic acid-(5-methoxy-2-methyl-4-nitro-anilide) 
• 99-21-8 2-methoxy-4-benzoylamino-5-methyl-aniline 
• 257933-82-7 pelitinib 
• 492456-86-7 N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-2-butenamide 
• 361162-95-0 6-amino-4-(3-chloro-4-fluoro-phenylamino)-7-ethoxy-quinoline-3-carbonitrile 
• 214485-68-4 4-(3-Bromo-phenylamino)-7-ethoxy-6-nitro-quinoline-3-carbonitrile 
• 214485-69-5 6-amino-4-(3-bromo-phenylamino)-7-ethoxy-quinoline-3-carbonitrile 
• 492456-51-6 (E)-2-Cyano-3-(3-ethoxy-4-nitro-phenylamino)-acrylic acid ethyl ester 
• 361162-92-7 2-acetylamino-4-ethoxy-5-nitrobenzoic acid 
• 214476-08-1 7-Ethoxy-4-hydroxy-6-nitro-quinoline-3-carbonitrile 
• 214476-09-2 4-Chloro-7-ethoxy-6-nitro-quinoline-3-carbonitrile 

Relevant articles and documents

PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS

Compounds of the formula I or II: wherein X, m, Ar, R1 and R2 are as defined herein. The subject compounds are useful for treatment of IRAK-mediated conditions.

USE OF CYANOQUINOLINES FOR TREATING OR INHIBITING COLONIC POLYPS

This invention provides a method of treating or inhibiting colonic polyps which comprises providing a compound of formula (1); wherein R1, R2, R3, R4, X, Y, and n are defined hereinbefore, or a pharmaceutically acceptable salt thereof.

Synthesis and structure-activity relationships of 6,7-disubstituted 4-anilinoquinoline-3-carbonitriles. The design of an orally active, irreversible inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) and the human epi

A series of of 6,7-disubstituted-4-anilinoquinoline-3-carbonitrile derivatives that function as irreversible inhibitors of EGFR and HER-2 kinases have been prepared. These inhibitors have, at the 6-position, butynamide, crotonamide, and methacrylamide Mic

Method of treating or inhibiting colonic polyps

This invention provides a method of treating or inhibiting colonic polyps which comprises providing a compound of formula 1 wherein:R1, R2, R3, R4, X, Y, and n are as defined hereinbefore, or a pharmaceutically acceptable salt thereof.