326915-70-2

Basic information

• Product Name: C₁₂H₁₁FN₂O₂
• CAS NO: 326915-70-2
• Molecular Weight: 234.23
• Mol File: 326915-70-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₂H₁₁FN₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₁₁FN₂O₂(326915-70-2)
• EPA Substance Registry System: C₁₂H₁₁FN₂O₂(326915-70-2)

Safety Data

• Hazardous Substances Data: 326915-70-2(Hazardous Substances Data)

Upstream product

• 105-56-6 ethyl 2-cyanoacetate 
• 371-40-4 4-fluoroaniline 
• 94-05-3 ethyl (ethoxymethylene)cyanoacetate 

Downstream Products

• 1240693-53-1 C₁₇H₁₁F₂N₃ 
• 1240693-54-2 C₁₈H₁₁F₄N₃ 
• 1240693-55-3 C₁₇H₁₀F₃N₃ 
• 1240693-56-4 C₁₈H₁₄FN₃O 
• 1240693-58-6 C₁₉H₁₆FN₃ 
• 1240693-59-7 C₁₇H₁₀F₃N₃ 
• 1240693-60-0 C₁₇H₁₀ClF₂N₃ 
• 61338-20-3 C₁₀H₅FN₂O 

Relevant articles and documents

Synthesis and cytotoxicity studies of quinoline-3-carbonitrile derivatives

A series of quinoline-3-carbonitrile derivatives were designed and synthesized. Their cytotoxicity in vitro against four cancer cell lines (A549, HT-29, MDA-MB-231 and SMMC-7721) were evaluated by standard MTT assay. The pharmacological results showed that most of the prepared compounds displayed excellent selective cytotoxicity toward SMMC-7721 cell line. Among them, compounds 7c, 7e, 11b, 11f and 11g were more active than Gefitinb against SMMC-7721 cell line.