327-95-7 Usage
Uses
Used in Pharmaceutical Industry:
4-Fluoroisophthalic acid is used as a building block for the synthesis of various pharmaceuticals, contributing to the development of new drugs with improved properties.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Fluoroisophthalic acid is utilized as a key intermediate for the preparation of agrochemicals, enhancing the effectiveness of these products in agricultural applications.
Used in Material Science:
4-Fluoroisophthalic acid is employed as a precursor for the production of functional materials, leveraging its unique chemical properties to create materials with specific characteristics for various applications.
Used in Dye Production:
4-Fluoroisophthalic acid is used as a starting material in the synthesis of fluorescent dyes, which are important in various fields such as bioimaging and diagnostics.
Used in Polymer Synthesis:
4-Fluoroisophthalic acid is used as a monomer in the production of polymers, which can exhibit special properties due to the presence of the fluorine atom, useful in high-performance materials.
Used in Coordination Chemistry:
In coordination chemistry, 4-Fluoroisophthalic acid is used in the formation of coordination complexes, which can have applications in catalysis, sensing, and other areas.
Check Digit Verification of cas no
The CAS Registry Mumber 327-95-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,2 and 7 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 327-95:
(5*3)+(4*2)+(3*7)+(2*9)+(1*5)=67
67 % 10 = 7
So 327-95-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H5FO4/c9-6-2-1-4(7(10)11)3-5(6)8(12)13/h1-3H,(H,10,11)(H,12,13)
327-95-7Relevant academic research and scientific papers
The first regioselective metalation and functionalization of unprotected 4-halobenzoic acids
Gohier, Frederic,Castanet, Anne-Sophie,Mortier, Jacques
, p. 1501 - 1504 (2007/10/03)
(Chemical Equation Presented) By treatment with s-BuLi, s-BuLi/TMEDA, or t-BuLi at ～-78°C, 4-fluoro- and 4-chlorobenzoic acids (1a,b) are metalated preferentially in the position adjacent to the carboxylate. A complete reversal in regioselectivity is observed for 1a when treated with LTMP; a sequential process involving a rapid intraaggregate lithiation through a quasi dianion complex "QUADAC" is postulated to explain the unusual reactivity of Me2S2 and I2.
TRICYCLIC DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
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Page 63, (2010/02/10)
The present invention relates to tricyclic derivatives or pharmaceutically acceptable salts thereof, their preparations and pharmaceutical compositions containing them. More precisely, the present invention relates to tricyclic derivatives as colchicine derivatives, pharmaceutically acceptable salts thereof, their preparations and pharmaceutical compositions containing them. Tricyclic derivatives of the present invention show very powerful cytotoxicity to cancer cell lines but were much less toxic than colchicine or taxol, confirmed through animal toxicity test. Tricyclic derivatives of the invention also decrease the volume and weight of a tumor and have a strong angiogenesis inhibiting activity in HUVEC cells. Thus, tricyclic derivatives of the present invention can effectively be used as an anticancer agent, anti-proliferation agent and an angiogenesis inhibitor.
