32704-08-8Relevant academic research and scientific papers
REAGENTS ABD SYNTHETIC METHODS-40 HALOSILANES/CHROMIUM TRIOXIDE AS EFFICIENT OXIDIZING REAGENTS
Aizpurua, J. M.,Juaristi, M.,Lecea, B.,Palomo, C.
, p. 2903 - 2912 (1985)
Synthetic utility of halosilanes-chromium trioxide reagents as excellent new oxidizing agents is described.They are highly efficient for the oxidation of alcohols to carbonyl compounds, for the oxidative coupling of mercaptans intodisulfides and for a mild cleavage of oximes to carbonyl compounds.Chlorotrimethylsilane-chromium trioxide has been shown to be an efficient oxidizing agent for the conversion of arylmethanes to benzaldehydes.The reagent is applied to the oxidative cleavage of some benzyl esters.A mild procedure for the iodination of organic compounds by means of in situ generated iodonium species from this reagent and molecular iodine is also described.
NEW COMPOUND
-
Paragraph 0316; 0332, (2019/11/26)
PROBLEM TO BE SOLVED: To provide a new compound that does not have structural similarity to ceramide and has excellent CERT inhibitory activity. SOLUTION: The present invention provides a new compound of structural formula (I). A bond group -X- is cis-cyclopropyl-, R1, R2, R3, R4, and R5 independently represent a hydrogen atom, a halogen atom, a linear or branched C1-C8 alkyl group that may have a halogen atom, or OR6. SELECTED DRAWING: Figure 1 COPYRIGHT: (C)2020,JPOandINPIT
A Novel Aromatic Iodination Method Using F2
Rozen, Shlomo,Zamir, Dov
, p. 3552 - 3555 (2007/10/02)
A new method for direct aromatic iodination with IF, made in situ from the corresponding elements, is described.Depending on the reaction time and temperature, mono- or polyiodination can be achieved.Even deactivated aromatic rings can be directly iodinated without the presence of any Friedel-Crafts catalyst.Sensitive groups such as aromatic aldehydes are not affected by the reagent.
STOICHIOMETRIC AND CATALYTIC OXIDATIVE IODINATION OF AROMATIC COMPOUNDS IN THE PRESENCE OF NITROGEN-CONTAINING OXIDIZING AGENTS IN AQUEOUS TRIFLUOROACETIC ACID
Makhon'kov, D. I.,Cheprakov, A. V.,Beletskaya, I. P.
, p. 2029 - 2035 (2007/10/02)
The conditions for oxidative monoiodination of benzene, halogenobenzenes, toluene, halogenotoluenes, and p-toluic acid in solvents based on trifluoroacetic acid were studied.Yields of the respective iodoarenes close to quantitative were obtained in systems containing 10-20 vol. percent of water in the solvent with equimolar amounts of alkali-metal metal iodides in relation to the substrate in the presence of stoichiometric (under anaerobic conditions) or catalytic (in the presence of oxygen or air) amounts of alkali-metal nitrates.The analogous reactions with nitrites can only be conducted under aerobic conditions.These iodinating systems are compared with systems based on acetic acid containing iodine and mixtures of sulfuric and nitric acids.The conditions for the iodination of toluene and for the transformations of the obtained iodotoluenes in the presence of nitrogen-containing oxidizing agents in trifluoroacetic acid solutions were studied in detail.It was shown that p-iodotoluene undergoes ipso-nitrodeiodination to a significant degree under these conditions.It is supposed that the iodinating agent in the investigated systems is trifluoroacetyl hypoiodite.Data on the assignment of the PMR spectra of the synthesized isomeric nitroiodotoluenes and chloroiodotoluenes by a simple additive method are given.
