327188-52-3

Upstream product

• 90-05-1 2-methoxy-phenol 
• 327188-51-2 3-(2-chloro-4-(4-chlorophenyl)-5-oxazolyl)-1-propanol 
• 10465-81-3 1,1'-(Azodicarbonyl)dipiperidin 
• 198064-79-8 methyl 5-(4-chlorophenyl)-4-hydroxy-5-oxopentanoate 
• 108-90-7 chlorobenzene 
• 71354-29-5 methyl 5-(4-chlorophenyl)-5-oxopentanoate 
• 1501-26-4 methyl 4-(chlorocarbonyl)butyrate 
• 198064-80-1 methyl 5-(4-chlorophenyl)-5-oxo-4-(phenyoxycarbonyloxy)pentanoate 
• 198064-81-2 methyl 3-[4-(4-chlorophenyl)-2-oxo-2,3-dihydro-5-oxazolyl]propionate 
• 198063-87-5 methyl 3-[2-chloro-4-(4-chlorophenyl)-5-oxazolyl]propionate 
• 89150-43-6 methyl 4-bromo-5-(4-chlorophenyl)-5-oxopentanoate 

Downstream Products

• 327188-91-0 ethyl 1-[4-(4-chlorophenyl)-5-[3-(2-methoxyphenoxy)propyl]-2-oxazolyl]imidazole-2-carboxylate 
• 327189-07-1 4-(4-chlorophenyl)-5-[3-(2-methoxyphenoxy)propyl]-2-(2-undecyl-1-imidazolyl)oxazole 
• 327188-61-4 4-(4-chlorophenyl)-2-(4,5-diphenyl-1-imidazolyl)-5-[3-(2-methoxyphenoxy)propyl]oxazole 
• 327188-53-4 4-(4-chlorophenyl)-5-[3-(2-methoxyphenoxy)propyl]-2-(1-methyl-2-imidazolylsulfanyl)oxazole 
• 327188-54-5 4-(4-chlorophenyl)-2-(3-hydroxy-1-propylsulfanyl)-5-[3-(2-methoxyphenoxy)propyl]oxazole 
• 327188-66-9 2-(1-benzotriazolyl)-4-(4-chlorophenyl)-5-[3-(2-methoxyphenoxy)propyl]oxazole 
• 327188-65-8 4-(4-chlorophenyl)-2-[N-(2-hydroxyethyl)-N-methylamino]-5-[3-(2-methoxyphenoxy)propyl]oxazole 
• 327188-71-6 4-(4-chlorophenyl)-2-dimethylamino-5-[3-(2-methoxyphenoxy)propyl]oxazole 
• 327188-64-7 4-(4-chlorophenyl)-2-(3-hydroxymethyl-1-piperidinyl)-5-[3-(2-methoxyphenoxy)propyl]oxazole 
• 327188-56-7 4-(4-chlorophenyl)-2-(4-morpholinyl)-5-[3-(2-methoxyphenoxy)propyl]oxazole 
• 327188-67-0 4-(4-chlorophenyl)-5-[3-(2-methoxyphenoxy)propyl]-2-(4-phenyl-1-piperazinyl)oxazole 

Relevant academic research and scientific papers

Neurotrophin production secretion promoting agent

A neurotrophin production/secretion promoting agent which comprises an azole derivative of the formula: wherein R1represents a halogen atom, a heterocyclic group which may optionally be substituted, a hydroxy group which may optionally be substituted, a thiol group which may optionally be substituted, or an amino group which may optionally be substituted; A represents an acyl group which may optionally be substituted, a heterocyclic group which may optionally be substituted, a hydroxy group which may optionally be substituted, or a carboxyl group which may optionally be esterified or amidated; B represents an aromatic group which may optionally be substituted; X represents oxygen atom, sulfur atom, or nitrogen atom which may optionally be substituted; and Y represents a divalent hydrocarbon group or heterocyclic group, or a salt thereof; which is useful as an agent for preventing or treating neuropathy.

Synthesis and biological activity of novel 5-(omega-aryloxyalkyl)oxazole derivatives as brain-derived neurotrophic factor inducers.

A novel series of 5-(omega-aryloxyalkyl)oxazole derivatives was prepared and their effects on brain-derived neurotrophic factor (BDNF) production were evaluated in human neuroblastoma (SK-N-SH) cells. Syntheses were performed by construction of an oxazole