32720-59-5

Upstream product

• 110-91-8 morpholine 
• 5465-09-8 3,4-dimethylcyclohexanone 

Downstream Products

• 117286-44-9 cyano-2-(dimethyl-4,5-morpholino-2cyclohexenylimino-1)-2-acetate de methyle 
• 117286-45-0 10-(2-methoxyethyl)-7,8-dimethyl-3-phenylbenzo[g]pteridine-2,4(3H,10H)-dione 

Relevant academic research and scientific papers

Nouvelle voie d'acces aux iso-alloxazines par l'intermediaire d'alkyl-1-amino-2-tetrahydro-1,5,6,7-quinoxaline-3-carbonitriles (ou carboxylate de methyle)

A new synthetic approach to iso-alloxazines using 1-alkyl-2-amino-1,5,6,7-tetrahydroquinoxaline-3-carbonitriles (or the corresponding methylcarboxylates) is reported.These key intermediates, accessible in two steps from cyclohexanone-enamines, when treated alkyl(aryl)iso-cyanates, guanidine or alkylchloroformates yield tetrahydro-iso-alloxazine derivatives, which can be dehydrogenated.Thus 3,10-dialkyl, 10-alkyl-3-aryl, 10-alkyl-iso-alloxazines or their 2-imino-4-oxo, 4-imino-2-oxo and 2,4-bisimino derivatives were obtained.The regiospecific aspect of this approach is illustrated by the synthesis of naphto, naphto or dimethyl-7,8 benzo pteridine derivatives.Tautomeric behavior or the tetrahydro intermediates and some limitations of the method are discussed.