32730-13-5

Upstream product

• 607-55-6 α-naphthyl benzoate 
• 90-15-3 α-naphthol 
• 70-11-1 α-bromoacetophenone 
• 70049-85-3 3-(4'-bromophenyl)naphtho-[1, 2-b]furan 
• 833485-56-6 (2-benzoyl-naphthalen-1-yloxy)-acetic acid ethyl ester 
• 21009-99-4 2-benzoyl-1-naphthol 
• 14621-59-1 2-(naphthalen-1-yloxy)-1-phenylethanone 

Downstream Products

• 91388-10-2 acetyl-2 phenyl-3 naphto<1,2-b>furanne 
• 91388-09-9 formyl-2 phenyl-3 naphto<1,2-b>furanne 

Relevant academic research and scientific papers

TfOH-SiO2 as an efficient and recyclable catalyst for synthesis of 3-arylbenzofurans

A convenient process for the synthesis of 3-arylbenzofurans and their derivatives by 2-phenoxy-1-phenylethanones via TfOH-SiO2 catalyzed is developed. This method provides several advantages such as simple work-up procedure, simple post-treatme

Synthesis of benzofurans from the cyclodehydration of α-phenoxy ketones mediated by Eaton’s reagent

Cyclodehydration of α-phenoxy ketones promoted by Eaton’s reagent (phosphorus pentoxide–methanesulfonic acid) is used to prepare 3-substituted or 2,3-disubstituted benzofurans with moderate to excellent yields under mild conditions. The method provides a facile access to benzofurans from readily available starting materials such as phenols and α-bromo ketones. The reaction is highly efficient, which is attributed to the good reactivity and fluidity of Eaton’s reagent. The reaction can be applied to prepare naphthofurans, furanocoumarins, benzothiophenes, and benzopyrans.

Titanium tetrachloride promoted cyclodehydration of aryloxyketones: Facile synthesis of benzofurans and naphthofurans with high regioselectivity

An efficient and facile method for the synthesis of a broad series of benzofurans and naphthofurans is described. The direct intramolecular cyclodehydration of aryloxyketones in the presence of titanium tetrachloride affords the corresponding benzofurans and naphthofurans with good regioselectivity and yields.

Method for synthesizing naphthofuran derivative by taking titanium tetrachloride as dehydrating agent

The invention discloses a method for preparing a naphthofuran derivative by taking naphthoxy ketone as a raw material through dehydrating cyclization under the action of titanium tetrachloride. Namely, under protection of inert gas, alpha-naphthoxy ketone

Novel one-pot synthesis of 3-Phenylnaphtho[2,3-b]furan and 3-phenylbenzofurans under microwave irradiation and solvent-free conditions

A one-pot synthesis of functionalized benzofurans has been developed via O-alkylation, carbon-carbon coupling/cyclization, and dehydration/olefination tandem reactions from phenacyl bromide and phenols under microwave irradiation and solvent-free conditio

Facile synthesis of regio-isomeric naphthofurans and benzodifurans

Naphtho[1,2-b]furans 1a-f, naphtho[2,1-b]furans 2a-f, benzo[1,2-b:5,4- b′]difurans 3a-b, benzo[1,2-b:4,5-b′]difurans 4a-b, and benzo[1,2-b:4,3-b′]difurans 5a-b were synthesized by base-catalyzed cyclization reaction of the corresponding o-alkoxybenzoylarene derivatives. The o-alkoxybenzoylarenes were obtained from the etherification reaction of the o-hydroxybenzoylarenes, which were prepared either by the reaction of methoxyarenes with benzoyl chloride in the presence of aluminum chloride or by photo-Fries rearrangement of aryl benzoates. Graphical Abstract.

Clay catalyzed facile cyclodehydration under microwave: Synthesis of 3-substituted benzofurans

The preparation of 3-substituted benzofurans from α-phenoxy acetophenones and related compounds using clay under microwave irradiation is described. The inexpensive, reusable clay and non-solvent reaction conditions are the important features of the proce

Three-step synthesis of an array of substituted benzofurans using polymer-supported reagents

An efficient combinatorial route to substituted 3-phenyl-benzofurans, is achieved by the bromination of acetophenones to α-bromoacetophenones by polymer-supported pyridinium bromide perbromide (PSPBP). The subsequent clean substitution of the obtained bromides by phenols using 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD-P) and cyclodehydration of the resulting α-phenoxyacetophenones using Amberlyst 15, affords pure products without the need for any chromatographic purification step.

Antimicrobial polycyclic nitrofurans

2-Nitrobenzofurans in which the furan ring is either fused to or substituted by a fused bicyclic system, which are active as antimicrobial agents, processes for their use and intermediates therefor are described.