32748-19-9

Upstream product

• 75-04-7 ethylamine 
• 698-16-8 benzohydroximoyl chloride 

Downstream Products

• 35608-06-1 N-(4-ethyl-3-phenyl-4H-[1,2,4]oxadiazol-5-ylidene)-toluene-4-sulfonamide 
• 35608-05-0 N-(4-ethyl-3-phenyl-4H-[1,2,4]oxadiazol-5-ylidene)-benzenesulfonamide 
• 35608-08-3 4-chloro-N-(4-ethyl-3-phenyl-4H-[1,2,4]oxadiazol-5-ylidene)-benzenesulfonamide 
• 65159-22-0 (4-ethyl-3-phenyl-4H-[1,2,4]oxadiazol-5-ylidene)-cyanamide 
• 64671-55-2 3-Phenyl-4-ethyl-Δ²-1,2,4-oxadiazolin-5-thion 
• 64671-79-0 4-Ethyl-3-phenyl-4H-[1,2,4]thiadiazol-5-one 
• 86339-17-5 C₁₆H₁₆N₂O₂ 
• 10480-41-8 4-ethyl-3-phenyl-4H-[1,2,4]oxadiazol-5-one 
• 35608-07-2 N-(4-ethyl-3-phenyl-4H-[1,2,4]oxadiazol-5-ylidene)-methanesulfonamide 

Relevant academic research and scientific papers

Insight into technetium amidoxime complex: Oxo technetium(V) complex of N-substituted benzamidoxime as new basic structure for molecular imaging

In search of benzamidoxime (BHam) derivatives that provide a single 99mTc-labeled compound of high in vivo stability, we synthesized three N-alkyl compounds of benzamidoxime (BHam) ligand. They provided a single 99mTc-labeled compound by ligand exchange reaction of 99mTc-glucoheptonate in high radiochemical yields (over 95% at MBHam concentration of 1 × 10-5 M). 99mTc-N-methyl benzamidoxime (99mTc-MBHam) showed higher stability than the parental 99mTc-BHam. The complex of this compound with 99gTcO+ ion was prepared, isolated, and characterized by FT-IR and NMR spectra as well as X-ray diffraction.99gTc-MBHam crystallized in an orthorhombic space group Pna2 1 with a = 13.4823(5), b = 15.5410(7), c = 7.7907(3) A, V = 1632.39(11) A3, and Z =4. The 99gTc complex possessed square base pyramid coordination geometry. The equatorial plane was formed by two-amine nitrogen and two-oxime oxygen atoms in trans position, while the oxo core of the technetium(V) occupied the apical position. The 99gTc-MBHam proved to be identical with the 99mTc-MBHam prepared at the no-carrier-added level by comparison of their HPLC profiles.