32749-01-2Relevant academic research and scientific papers
BIOMIMETIC OXIDATIONS OF BENZYLISOQUINOLINE ALKALOUDS. II. THE BIS(SALICYLALDEHYDE)ETHYLENEDIIMINECOBALT(II)-CATALYZED OXIDATION OF BENZYLISOQUINOLINES WITH OXYGEN
Canonica, Luigi,Galliani, Guido,Nali, Micaela,Rindone, Bruno,Tollari, Stefano
, p. 7 - 12 (2007/10/02)
The complex bis(salicylaldehyde)ethylenediiminecobalt(II) (CoII salen) catalyzes the oxidation of benzylisoquinoline alkaloids with oxygen.Aminium radicals are formed and give rise to 1,2-dehydrobenzylisoquinoline ions.Cleavage of the C(1)-C(9) bond via C(9) oxidation is observed in some instances.
BIOMIMETIC OXIDATIONS OF BENZYLISOQUINOLINE ALKALOUDS. I. THE PEROXIDASE AND ASCORBIC OXIDASE-CATALYSED OXIDATION
Canonica, Luigi,Nali, Micaela,Rindone, Bruno,Tollari, Stefano,Marchesini, Augusto
, p. 1 - 6 (2007/10/02)
The enzyme peroxidase behaves as a mixed-function oxidase toward the benzylisoquinoline alkaloid nucleus, giving rise to various phenoxy radicals depending on the substrate.These give either C(4) hydroxylation or C(5') hydroxylation and cyclisation to an aporphine, or cleavage of the C(1)-C(9) bond.
