327630-01-3

Upstream product

• 327629-88-9 1-((R)-(E)-3-Iodo-prop-1-ene-1-sulfinyl)-4-methyl-benzene 
• 266322-00-3 (2E,R_S)-methanesulfonic acid 3-(tolyl-4-sulfinyl)-allyl ester 
• 105-53-3 diethyl malonate 
• 92210-74-7 (E)-3-((R)-Toluene-4-sulfinyl)-prop-2-en-1-ol 
• 152547-42-7 2-(bromomethyl)-3-((tert-butyldimethylsilyl)oxy)-4H-pyran-4-one 
• 327629-92-5 C₁₉H₂₂F₃NO₆S 

Relevant academic research and scientific papers

Reversal of stereoselectivity in [5 + 2] pyrone-alkene cycloadditions using a sulfoxide-to-sulfoximine switch. Enantiodivergent synthesis of 8-oxabicyclo[3.2.1]octane systems

(Matrix presented) Switching from a sulfinyl to a sulfonimidoyl group allows the reversal of the sense of asymmetric induction in thermal [5C + 2C] intramolecular pyrone-alkene cycloadditions. Removal of the sulfoximine unit from the resulting cycloadduct

A practical route to enantiopure, highly functionalized seven-membered carbocycles and tetrahydrofurans: Concise synthesis of (+)-nemorensic acid

Highly diastereoselective thermal [5C+2C] intramolecular pyrone-alkene cycloadditions can be achieved by introducing a homochiral p-tolylsulfinyl group at a suitable position of the alkene. The resulting adducts can be readily desulfinylated to give optic