32768-97-1

Basic information

• Product Name: Friedelane-1,3-dione
• Synonyms: Friedelane-1,3-dione
• CAS NO: 32768-97-1
• Molecular Formula: C30H48O2
• Molecular Weight: 440.70092
• Mol File: 32768-97-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Friedelane-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: Friedelane-1,3-dione(32768-97-1)
• EPA Substance Registry System: Friedelane-1,3-dione(32768-97-1)

Safety Data

• Hazardous Substances Data: 32768-97-1(Hazardous Substances Data)

Upstream product

• 1255647-99-4 1β-hydroxy-3-oxo-D:A-friedooleanane 

Downstream Products

• 43230-72-4 friedelan-1-one 
• 559-73-9 D:A-friedo-oleanane 
• 43230-67-7 3-methoxyfriedel-2-en-1-one 

Relevant articles and documents

Triterpenes from Garcia parviflora. Cytotoxic evaluation of natural and semisynthetic friedelanes

Three new friedelane-type triterpenes, 1,2-dehydro-2,3-secofriedelan-3-oic acid (1), 1β-hydroxyfriedelin (2), and 3β-hydroxyfriedelan-23-oic acid (3), and the known compounds friedelin-3,4-lactone (4), acetyl aleuritolic acid (5), 4-hydroxy-5-propionyl-1,3-di-O-methylpyrogallol, elemicin, and (-)-syringaresinol were isolated from the leaves of Garcia parviflora. The structures of 1-3 were elucidated by spectroscopic methods, including 1D and 2D NMR, HREIMS, X-ray, and CD analysis. Some derivatives of 2 (6-14) were prepared via oxidation, reduction, and esterification. The natural triterpenes and the semisynthetic friedelane derivatives were tested for cytotoxic activity against human cancer cell lines U251, PC-3, K562, HCT-15, MCF-7, and SKLU-1. Compound 5 was cytotoxic against U251 cells.