328-69-8

Basic information

• Product Name: 3-HYDROXY-5-(TRIFLUOROMETHYL)BENZOIC ACID
• Synonyms: 3-HYDROXY-5-(TRIFLUOROMETHYL)BENZOIC ACID;3-Carboxy-5-(trifluoromethyl)phenol, 3-Carboxy-5-hydroxybenzotrifluoride
• CAS NO: 328-69-8
• Molecular Formula: C₈H₅F₃O₃
• Molecular Weight: 206.12
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 328-69-8.mol

Chemical Properties

• Melting Point: 191-193°C
• Boiling Point: 333.7°Cat760mmHg
• Flash Point: 155.6°C
• Appearance: /
• Density: 1.539g/cm³
• Vapor Pressure: 5.32E-05mmHg at 25°C
• Refractive Index: 1.509
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 3.65±0.10(Predicted)
• CAS DataBase Reference: 3-HYDROXY-5-(TRIFLUOROMETHYL)BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-HYDROXY-5-(TRIFLUOROMETHYL)BENZOIC ACID(328-69-8)
• EPA Substance Registry System: 3-HYDROXY-5-(TRIFLUOROMETHYL)BENZOIC ACID(328-69-8)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 328-69-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Manufacturing:
3-Hydroxy-5-(trifluoromethyl)benzoic acid is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with enhanced properties. Its unique trifluoromethyl group can improve the pharmacokinetics and pharmacodynamics of the resulting compounds.
Used in Agrochemical Production:
In the agrochemical industry, 3-Hydroxy-5-(trifluoromethyl)benzoic acid is utilized as a key component in the creation of pesticides and other crop protection agents. Its incorporation can lead to the design of more effective and targeted agrochemicals.
Used in Organic Synthesis:
3-Hydroxy-5-(trifluoromethyl)benzoic acid serves as a versatile precursor for the synthesis of complex organic molecules. Its presence in chemical reactions can facilitate the formation of a variety of organic compounds, contributing to the advancement of chemical research and development.
Used in Chemical Research and Development:
As an important compound in the field, 3-Hydroxy-5-(trifluoromethyl)benzoic acid is employed in research to explore its potential applications and to understand its reactivity and properties. This helps in the discovery of new chemical processes and the creation of innovative materials.

InChI:InChI=1/C8H5F3O3/c9-8(10,11)5-1-4(7(13)14)2-6(12)3-5/h1-3,12H,(H,13,14)

Upstream product

• 328-68-7 3-amino-5-(trifluoromethyl)benzoic acid 
• 328-80-3 3-nitro-5-trifluoromethyl-benzoic acid 
• 53985-39-0 3-(benzyloxy)-5-(trifluoromethyl)benzoic acid 
• 161622-05-5 3-fluoro-5-(trifluoromethyl)benzoic acid 
• 250682-12-3 ethyl 3-fluoro-5-(trifluoromethyl)benzoate 

Downstream Products

• 1246522-57-5 3-hydroxy-5-(trifluoromethyl)benzoyl chloride 

Relevant articles and documents

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HETEROCYCLIC INHIBITORS OF THE SODIUM CHANNEL

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FUSED HETEROCYCLIC COMPOUND

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