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1-Butoxy-3,5-bis(trifluoromethyl)benzene is an organic compound characterized by a benzene ring with a butoxy group attached to the 1-position and two trifluoromethyl groups at the 3 and 5 positions. This chemical features a molecular formula of C12H13F6O and a molecular weight of 294.22 g/mol. The compound is known for its unique properties, such as its low boiling point and high reactivity, which make it useful in various chemical reactions and applications, particularly in the synthesis of pharmaceuticals and agrochemicals. Its structure provides a balance of lipophilicity and polarity, which can influence its solubility and interaction with other molecules.

328-78-9

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328-78-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 328-78-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,2 and 8 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 328-78:
(5*3)+(4*2)+(3*8)+(2*7)+(1*8)=69
69 % 10 = 9
So 328-78-9 is a valid CAS Registry Number.

328-78-9Downstream Products

328-78-9Relevant academic research and scientific papers

Light-Promoted Nickel Catalysis: Etherification of Aryl Electrophiles with Alcohols Catalyzed by a NiII-Aryl Complex

Cao, Rui,Lai, Chu-Hui,Li, Gang,Liu, Fengyi,Lu, Huan-Huan,Wang, Chao,Xiao, Jianliang,Xue, Dong,Yang, Liu,Zhang, Wei

, p. 12714 - 12719 (2020)

A highly effective C?O coupling reaction of (hetero)aryl electrophiles with primary and secondary alcohols is reported. Catalyzed by a NiII-aryl complex under long-wave UV (390–395 nm) irradiation in the presence of a soluble amine base without any additional photosensitizer, the reaction enables the etherification of aryl bromides and aryl chlorides as well as sulfonates with a wide range of primary and secondary aliphatic alcohols, affording synthetically important ethers. Intramolecular C?O coupling is also possible. The reaction appears to proceed via a NiI–NiIII catalytic cycle.

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