328084-37-3Relevant academic research and scientific papers
Rapid Chemical Synthesis of Self-Assembling Semi-Synthetic Proteins
Bhandari, Pavankumar Janardhan,Rao, Kasuladevu Jegannadha,Reddy, Mullapudi Mohan,Sandanaraj, Britto S.
, p. 8576 - 8589 (2021/07/19)
The design of well-defined monodispersed self-assembling semi-synthetic proteins is emerging as a promising research avenue. These proteins hold great potential to be used as scaffolds for various protein nanotechnology applications. Currently, there are very few chemical methods reported; however, they suffer from elaborate multistep organic synthesis. Herein, we report a new chemical methodology for the rapid synthesis of a diverse set of semi-synthetic protein families, which include protein amphiphiles, facially amphiphilic protein-dendron conjugates, and pH-sensitive protein-dendron conjugates. This chemical method holds great potential to access a wide variety of semi-synthetic proteins in a short time.
Fluorophore-cored dendrimers for patterns in metalloprotein sensing
Jiwpanich, Siriporn,Sandanaraj, Britto S.,Thayumanavan
supporting information; experimental part, p. 806 - 808 (2009/07/10)
In fluorophore-cored dendrimers with peripheral binding functionalities, the effect of generation upon protein binding-induced fluorescence quenching can be unpredictable; this is because the increase in fluorophore-binding functionality distance with gen
ELECTROCHEMICAL AFFINITY BIOSENSOR SYSTEM AND METHODS
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Sheet 28, (2010/02/11)
The present invention provides novel osmium-based electrochemical species for the detection of wide variety of analytes using immunological techniques. The present invention also provides diagnostic kits and test sensors supporting electrode structures that can be used with the osmium-based electrochemical species. The test sensor can be fabricated to support interdigitated arrays of electrodes that have been designed to provide amplification of the electrical signal amplification desired to analyze analytes that may be present at low concentrations.
