32816-69-6Relevant articles and documents
Catalyst-free straightforward synthesis of 3-cyano-3-arylamino-2-oxindoles through hydrocyanation with benzoyl cyanide
Chen, Xiao,Li, Zheng
, p. 686 - 693 (2020)
The effective hydrocyanation of 3-(arylimino)indolin-2-ones with benzoyl cyanide under catalyst-free condition at room temperature to synthesize 3-cyano-3-arylamino-2-oxindoles is described. This protocol benefits from low toxicity, inexpensive, and easy-to-handle cyanating agent, no catalysts, no additives, mild conditions, good substrate tolerance, and simple work-up procedure. This reaction successfully offers an alternative to structurally diverse 3,3-disubstituted oxindoles.
