32816-75-4Relevant academic research and scientific papers
Synthesis, characterization, and antimicrobial activity of new benzofuran derivatives
Kenchappa,Bodke, Yadav D.,Telkar, Sandeep,Sindhe, M. Aruna,Giridhar
, p. 2827 - 2836 (2017/03/22)
A novel series of (5-substituted-1-benzofuran-2-yl)(2,4-substituted phenyl)methanones (4a–4i) have been prepared by the Knoevenagel condensation of (5-substituted-1-benzofuran-2-yl)(2,4-substituted phenyl)methanone (3a–3i) with Meldrum’s acid. The structu
Synthesis and antitubercular activity of 4-thiazolidinone derivatives incorporating benzofuran moiety
Basawaraj, Raga,Channamma,Sangmeshwar
, p. 59 - 66 (2019/01/21)
5-Bromo-1-benzofuran-2-yl(substituted phenyl) methanones (2a-e) were prepared by the reaction of 2-bromo-1-(phenyl) ethanones and 5-bromosalicylaldehyde in dimethylformamide in the presence of anhydrous potassium carbonate to maintain basic condition. Con
Reaction products of 5-bromobenzofuran-2-yl-aryl methanone and their antimicrobial activities
Ali, Syed Sarfraz,Channamma,Basawaraj, Raga
, p. 189 - 196 (2019/01/21)
5-Bromobenzofuran-2-yl-aryl methanones (2a-e) were obtained by the reaction of 5-bromosalicylaldehyde 1 with 2-bromo-1-(aryl) ethanones. The condensation of compounds (2a-e) with hydroxylamine hydrochloride, thiosemicarbazide and aromatic amine such as an
DMAP-catalyzed cascade reaction: One-pot synthesis of benzofurans in water
Shang, Yongjia,Wang, Cuie,He, Xinwei,Ju, Kai,Zhang, Min,Yu, Shuyan,Wu, Jiaping
experimental part, p. 9629 - 9633 (2011/01/03)
A series of benzofurans were efficiently synthesized in good to excellent yields using 4-dimethylaminopyridine (DMAP) catalyzed cascade reaction between salicylaldehydes and halogenated ketones in water at 80 °C opened atmosphere.
Preparation of 2-, 3-, 4- and 7-(2-alkylcarbamoyl-1-alkylvinyl)benzo[b] furans and their BLT1 and/or BLT2 inhibitory activities
Ando, Kumiko,Kawamura, Yoko,Akai, Yukiko,Kunitomo, Jun-Ichi,Yokomizo, Takehiko,Yamashita, Masayuki,Ohta, Shunsaku,Ohishi, Takahiro,Ohishi, Yoshitaka
, p. 296 - 307 (2008/09/21)
Several 2-alkylcarbamoyl-1-alkylvinylbenzo[b]furans were designed to find a selective leukotriene B4 (LTB4) receptor antagonist. 2-(2-Alkylcarbamoyl-1-alkylvinyl)benzo[b]furans having a substituent group at the 3-position, 4-(2-alkylcarbamoyl-1-methylvinyl)benzo[b]furans having a substituent group at the 3-position, and 7-(2-alkylcarbamoyl-1-methylvinyl) benzo[b]furans and 3-(2-alkylcarbamoyl-1-alkylvinyl)benzo[b]furans were prepared and evaluated for LTB4 receptor (BLT1 and BLT 2) inhibitory activities. (E)-3-Amino-4-[2-[2-(3,4-dimethoxyphenyl) ethylcarbamoyl]-1-methylvinyl]benzo[b]furan ((E)-17c) showed potent and selective inhibitory activity for BLT2. On the other hand, (E)-7-(2-diethylcarbamoyl-1-methylvinyl)benzo[b]furan ((E)-27a) showed potent inhibitory activity for both BLT1 and BLT2. This journal is The Royal Society of Chemistry.
Microwave-mediated solvent free Rap-Stoermer reaction for efficient synthesis of benzofurans
Rao, Maddali L.N.,Awasthi, Dheeraj K.,Banerjee, Debasis
, p. 431 - 434 (2008/02/03)
The Rap-Stoermer reaction of salicylaldehydes with diverse phenacyl bromide and phenacyl iodides proceeded cleanly to afford various functionalized benzofurans in excellent yields under base-mediated solvent free microwave irradiation conditions.
Reaction of chalcones with NBS, a simple one pot synthesis of 2-aroylbenzo[b]furanes
Litkei, Gyoergy,Gulacsi, Katalin,Antus, Sandor,Dinya, Zoltan
, p. 3061 - 3074 (2007/10/03)
A simple one pot synthesis of 2-aroylbenzo[b]furanes has been achieved by bromomethoxylation with NBS and subsequent treatment of the appropriately substituted 2-hydroxychalcones with sodium hydroxide.
