328237-98-5Relevant academic research and scientific papers
6-Hydroxy-1,3-dioxin-4-ones as non-peptidic HIV protease inhibitors
Lee, Yong Sup,Lee, Yong Sil,Lee, Jae Yeol,Kim, Sun Nam,Lee, Chong-Kyo,Park, Hokoon
, p. 2625 - 2627 (2000)
HIV protease inhibitors containing 6-hydroxy-1,3-dioxin-4-one ring system as a new scaffold have been prepared. Among them, compound 4d showed potent HIV protease inhibitory activity (IC50=0.01 μM) and antiviral activity in cell culture (ECsub
