328237-99-6

Basic information

• Product Name: 6-hydroxy-5-[1-(3-nitro-phenyl)-propyl]-2-phenethyl-2-propyl-[1,3]dioxin-4-one
• Synonyms: 6-hydroxy-5-[1-(3-nitro-phenyl)-propyl]-2-phenethyl-2-propyl-[1,3]dioxin-4-one
• CAS NO: 328237-99-6
• Molecular Weight: 425.481
• Mol File: 328237-99-6.mol

Chemical Properties

• CAS DataBase Reference: 6-hydroxy-5-[1-(3-nitro-phenyl)-propyl]-2-phenethyl-2-propyl-[1,3]dioxin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-hydroxy-5-[1-(3-nitro-phenyl)-propyl]-2-phenethyl-2-propyl-[1,3]dioxin-4-one(328237-99-6)
• EPA Substance Registry System: 6-hydroxy-5-[1-(3-nitro-phenyl)-propyl]-2-phenethyl-2-propyl-[1,3]dioxin-4-one(328237-99-6)

Safety Data

• Hazardous Substances Data: 328237-99-6(Hazardous Substances Data)

Upstream product

• 328237-98-5 2-phenethyl-2-propyl-[1,3]dioxane-4,6-dione 
• 29898-25-7 1-phenylhexan-3-one 
• 97-93-8 triethylaluminum 

Downstream Products

• 328238-00-2 5-[1-(3-amino-phenyl)-propyl]-6-hydroxy-2-phenethyl-2-propyl-[1,3]dioxin-4-one 

Relevant articles and documents

6-Hydroxy-1,3-dioxin-4-ones as non-peptidic HIV protease inhibitors

HIV protease inhibitors containing 6-hydroxy-1,3-dioxin-4-one ring system as a new scaffold have been prepared. Among them, compound 4d showed potent HIV protease inhibitory activity (IC50=0.01 μM) and antiviral activity in cell culture (ECsub