3283-79-2

Upstream product

• 41784-08-1 4-acetylbenzenaminium hydrochloride 
• 99-92-3 p-aminobenzophenone 

Downstream Products

• 20412-18-4 1-[4-[(E)-2-(4-methoxyphenyl)vinyl]phenyl]ethanone 
• 123692-97-7 5-(4-acetylphenylazo)salicylaldehyde 
• 31485-43-5 ethyl (E)-2-(2-(4-acetylphenyl)hydrazono)propanoate 
• 128381-10-2 1-(4-{N'-[1-Nitro-1-phenyl-meth-(Z)-ylidene]-hydrazino}-phenyl)-ethanone 
• 79643-60-0 9-(4-acetylphenylazo)julolidine 
• 82588-03-2 9-[(4-Acetyl-phenyl)-hydrazono]-6-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acid 
• 99-91-2 para-chloroacetophenone 
• 90476-01-0 1-p-acetylphenyl-3-ethyl-3-hydroxymethyltriazene 
• 70346-60-0 1-p-acetylphenyl-3-hydroxymethyl-3-methyltriazene 
• 87450-06-4 N,N-bis(1-p-acetylphenyl-3-methyltriazen-3-ylmethyl) methylamine 
• 1788-10-9 4-Acetylbenzenesulfonyl chloride 
• 220606-58-6 C₁₅H₁₃ClN₂O₃S 
• 139455-65-5 N-(4-acetylphenyl) 2-oxopropanehydrazonoyl chloride 
• 13329-40-3 4-Iodoacetophenone 

Relevant academic research and scientific papers

Synthesis and Biological Evaluation of Novel Bischalcone Derivatives as Carbonic Anhydrase Inhibitors

Design and synthesis of a new type of bischalcones as an alternative to natural and synthetic bischalcones are reported for the first time. Key steps involved the solvent-free Claisen–Schmidt condensation of chalcones, and the successful first application

Synthesis, nature of electronic transitions, and absorption spectra of the dye based on 4-(methyl-1-{2-[4-(1-methyl-2-oxo-1,2-dihydroquinolin-3-yl)phenyl]-2-oxoethyl}pyridinium bromide

The reaction of 3-(4-bromoacetylphenyl)-1-methylquinolin-2(1Н)-one with pyridine and 4-methylpyridine has afforded the corresponding pyridinium salts. Condensation of 4-methyl-1-{2-[4-(1-methyl-2-oxo-1,2-dihydroquinolin-3-yl)phenyl]-2-oxoethyl}pyridinium

Synthesis and characterization for new Zn(II) complexes and their optimizing fertilization performance in planting corn hybrid

Novel Zn(II)–benzohydrazide complexes have been synthesized using Zn(NO3)2·6H2O salt. All new synthesises were investigated by available analytical and spectral tools to demonstrate their formulae. Binuclear complexes were

Synthesis and bioactivity evaluation of eugenol hybrids obtained by Mannich and 1,3 dipolar cycloaddition reactions

Design, synthesis, and bioactivity evaluation of novel mannich bases (2a-2j) and triazole-chalcone derivatives (7a-7k) of Eugenol 1 were reported. Among all the derivatives tested for antiproliferative activity, di-amine manich derivative 2b (32.92 μM), a

Synthesis and Pharmacological Investigations of Novel Pyrazolyl and Hydrazonoyl Cyanide Benzimidazole Entities

Various novel benzimidazole entities linked to pyrazolyl and hydrazonoyl cyanide substrates carrying aryl and heteroaryl groups (8a–e to 10a–e) were synthesized using new route syntheses and were focused on their pharmacological evaluation as one of the m

New biscyanine dye based on 1-{2-oxo-2-[4-(2-oxo-2H-chromen-3-yl)phenyl]ethyl}-4-methylpyridinium bromide. Electron transitions and electronic spectra

New biscyanine dye, 4-{2-[4-(dimethylamino)phenyl]ethenyl}-1-{2-[4-(dimethylamino)phenyl]-1-[4-(2-oxo-2H-chromen-3-yl)benzoyl]ethenyl}pyridinium bromide, has been prepared via condensation of 4-dimethylaminobenzaldehyde with 4-methyl-1-{2-oxo-2-[4-(2-oxo-2H-chromen-3-yl)phenyl]ethyl}pyridinium bromide. The latter has been synthesized via the Meerwein reaction of coumarin with 4-acetylphenyldiazonium chloride with subsequent bromination and quaternization of the formed α-bromoketone under the action of 4-methylpyridine. Electronic spectra are analyzed, and quantum-chemical simulation of possible isomers of the biscyanine dye has been performed.

Synthesis of nitrogen heterocycles underlain by application of 3-(4-acetyl[phenyl)-2h-coumarin

3-(4-Acetylphenyl)-2H-chromen-2-one was obtained from 4- acetylphenyldiazonium chloride in the conditions of Meerwein reaction. Reactions of 3-[4-(2-bromoacetyl)phenyl]-2H-chromen-2-one with pyridine, 4-methylpyridine, quinoline, benzo[f]quinoline, and triphenylphosphine afforded quaternary salts, and with thioacetamide, thiourea, 2-aminopyridine, 2-aminopyrimidine, and 6-aminopurine provided the corresponding derivatives of thiazole, imidazo[1,2-a]pyridine, imidazo[1,2-a]pyrimidine, imidazo[2,1-i] purine. In the reaction of the same bromo derivative with thiosemicarbazide and aromatic aldehydes a thiazole ring is built and the corresponding hydrazones are formed. Pleiades Publishing, Ltd., 2013.

Novel azo dyes derived from 8-methyl-4-hydroxyl-2-quinolone: Synthesis, UV-vis studies and biological activity

In this study, N,N′-di-(2-methylphenyl)malonamide was synthesized and reacted with polyphosphoric acid to afford 8-methyl-4-hydroxyl-2-quinolone. Eight novel azo disperse dyes were then synthesized by linking diazotized p-substituted aniline derivatives w

Synthesis and study of new mesogenic homologous series : 4-(4′-n-Alkoxy benzoyloxy)-3-chlorophenylazo-4″-acetylbenzenes

A new homologous series of liquid crystals viz. 4-(4′-n-alkoxy benzoyloxy)-3-chlorophenylazo-4″-acetylbenzenes are studied with a view to understand mesomorphic characteristics of the molecule. The nematic mesophase appeared as threaded type of texture. The first five and sixteenth homologues are nonmesomorphic. Mesomorphic property commences from the sixth member of the series as nematic type without exhibition of any smetic property. Transition temperatures are observed through hot stage polarizing microscope. Analytical data supports the structure.

Synthetic Studies on Indoles and Related Compounds. XV. An Unusual Acylation of Ethyl Indole-2-Carboxylate in the Friedel-Crafts Acylation

The Friedel-Crafts reaction of ethyl indole-2-carboxylate (1a) with acyl chlorides or acid anhydrides in the presence of Lewis acids was investigated in order to establish a preparative procedure for the corresponding ethyl 3-acylindole-2-carboxylates (4).Although monoacylation occured successfully, the products were generally a mixture of ethyl 3-, 5-, and 7-acylindole-2-carboxylates (4,5 and 6).The ratio of the yields of these three products varied greatly depending on reaction conditions and reagents used.A tendency that the 3-acylindole (4) was obtained as a main product was observed when a Lewis acid other than aluminum chloride was used as a catalyst and/or an acyl chloride derived from a weaker acid was employed, whereas a tendency for formation of the 5- and 7-acylindoles (5 and 6) was observed when aluminum chloride and/or an acyl chloride derived from a stronger acid was used.As to the 5- and 7-acylindoles (5 and 6) , the yields of the former were always much higher than those of the latter (6).The result indicates that ethyl 3- and 5-acylindole-2-carboxylates can be regioselectively prepared from a common substrate (1a) by changing the reaction conditions or reagents. friedel-craft acylation; ethyl indole-2-carboxylate; acyl chloride; acid anhydride; lewis acid; aluminum chloride; acylindole