328314-29-0

Basic information

• Product Name: 4-benzyloxycarbonyl-6,7-dimethoxy-4-(2,4,6-trimethoxyphenyl)-2H-1-benzopyran-3(4H)-one
• Synonyms: 4-benzyloxycarbonyl-6,7-dimethoxy-4-(2,4,6-trimethoxyphenyl)-2H-1-benzopyran-3(4H)-one
• CAS NO: 328314-29-0
• Molecular Weight: 508.525
• Mol File: 328314-29-0.mol

Chemical Properties

• CAS DataBase Reference: 4-benzyloxycarbonyl-6,7-dimethoxy-4-(2,4,6-trimethoxyphenyl)-2H-1-benzopyran-3(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-benzyloxycarbonyl-6,7-dimethoxy-4-(2,4,6-trimethoxyphenyl)-2H-1-benzopyran-3(4H)-one(328314-29-0)
• EPA Substance Registry System: 4-benzyloxycarbonyl-6,7-dimethoxy-4-(2,4,6-trimethoxyphenyl)-2H-1-benzopyran-3(4H)-one(328314-29-0)

Safety Data

• Hazardous Substances Data: 328314-29-0(Hazardous Substances Data)

Upstream product

• 36896-62-5 (2,4,6-trimethoxyphenyl)lead triacetate 
• 328314-20-1 4-benzyloxycarbonyl-6,7-dimethoxy-2H-1-benzopyran-3(4H)-one 
• 328314-11-0 6,7-dimethoxy-4-methoxycarbonyl-2H-1-benzopyran-3(4H)-one 
• 97341-39-4 methyl (2-methoxycarbonylmethoxy-4,5-dimethoxyphenyl)acetate 
• 70874-62-3 4,5-dimethoxy-2-hydroxy phenylacetic acid 

Downstream Products

• 328314-32-5 6,7-dimethoxy-4-(2,4,6-trimethoxyphenyl)-2H-1-benzopyran-3(4H)-one 

Relevant articles and documents

Synthesis of neoflavenes by ligand coupling reactions with aryllead triacetates

The reaction of 4-methoxycarbonylchroman-3-one with aryllead triacetates gave the 4-aryl derivatives after 3-4h reaction times in moderate to good yields. Unexpectedly, 2,4-diarylated derivatives were also obtained after longer reaction times. The activating methyl ester group proved difficult to remove by standard decarboxylation procedures. 4-Benzyloxycarbonylchroman-3-ones were therefore prepared and reacted with aryllead triacetates to afford the corresponding 4-aryl derivatives. These were subsequently decarboxylated, reduced and dehydrated to afford neoflavenes in modest overall yields.