97341-39-4

Basic information

• Product Name: methyl (2-methoxycarbonylmethoxy-4,5-dimethoxyphenyl)acetate
• CAS NO: 97341-39-4
• Molecular Weight: 298.293
• Mol File: 97341-39-4.mol

Chemical Properties

• CAS DataBase Reference: methyl (2-methoxycarbonylmethoxy-4,5-dimethoxyphenyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (2-methoxycarbonylmethoxy-4,5-dimethoxyphenyl)acetate(97341-39-4)
• EPA Substance Registry System: methyl (2-methoxycarbonylmethoxy-4,5-dimethoxyphenyl)acetate(97341-39-4)

Safety Data

• Hazardous Substances Data: 97341-39-4(Hazardous Substances Data)

Upstream product

• 70874-62-3 4,5-dimethoxy-2-hydroxy phenylacetic acid 
• 186581-53-3 diazomethane 
• 41743-39-9 4,5-dimethoxy-2-carboxymethoxyphenylacetic acid 

Downstream Products

• 328314-29-0 4-benzyloxycarbonyl-6,7-dimethoxy-4-(2,4,6-trimethoxyphenyl)-2H-1-benzopyran-3(4H)-one 
• 328314-28-9 4-benzyloxycarbonyl-6,7-dimethoxy-4-(2,4-dimethoxyphenyl)-2H-1-benzopyran-3(4H)-one 
• 328314-27-8 4-benzyloxycarbonyl-6,7-dimethoxy-4-(4-methoxyphenyl)-2H-1-benzopyran-3(4H)-one 
• 328314-32-5 6,7-dimethoxy-4-(2,4,6-trimethoxyphenyl)-2H-1-benzopyran-3(4H)-one 
• 328314-20-1 4-benzyloxycarbonyl-6,7-dimethoxy-2H-1-benzopyran-3(4H)-one 

Relevant articles and documents

Synthesis of neoflavenes by ligand coupling reactions with aryllead triacetates

The reaction of 4-methoxycarbonylchroman-3-one with aryllead triacetates gave the 4-aryl derivatives after 3-4h reaction times in moderate to good yields. Unexpectedly, 2,4-diarylated derivatives were also obtained after longer reaction times. The activating methyl ester group proved difficult to remove by standard decarboxylation procedures. 4-Benzyloxycarbonylchroman-3-ones were therefore prepared and reacted with aryllead triacetates to afford the corresponding 4-aryl derivatives. These were subsequently decarboxylated, reduced and dehydrated to afford neoflavenes in modest overall yields.