32856-88-5Relevant academic research and scientific papers
Catalytic, enantio- and diastereoselective synthesis of γ-butyrolactones incorporating quaternary stereocentres
Manoni, Francesco,Cornaggia, Claudio,Murray, James,Tallon, Sean,Connon, Stephen J.
supporting information; experimental part, p. 6502 - 6504 (2012/07/31)
A new, highly enantio- and diastereoselective catalytic asymmetric formal cycloaddition of aryl succinic anhydrides and aldehydes which generates paraconic acid (γ-butyrolactone) derivatives is reported.
Functionalized heterocycles as modulators of chemokine receptor function and methods of use therefor
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, (2008/06/13)
Disclosed are novel compounds having the formula or a physiologically acceptable salt, amide, ester or prodrug thereof. The compounds can be used to modulate (antagonize, agonize) chemokine receptor function. Also disclosed is a method for treating a patient having an inflammatory disease and/or viral infection comprising administering an effective amount of a compound of Formula I. In particular embodiments, the invention is a method for treating a patient infected with HIV.
