328575-23-1Relevant academic research and scientific papers
New derivatives of the 1,2-benzodiazepine ring system
Knight, David W.,Little, Paul B.
, p. 3752 - 3757 (2000)
The adducts 10, formed in high yield by condensations between the benzotriazole dianion 2 and enals 9, undergo smooth oxidation by manganese(IV) oxide to provide the expected conjugated enones. These then cyclise at varying rates, depending upon the subst
A new 1,2,3-triazolo[1,2]benzodiazepine ring system
Knight, David W.,Little, Paul B.
, p. 5037 - 5040 (2007/10/03)
Dianion 2 derived from N-Boc-aminobenzotriazole 1 condenses in a [1.2]fashion with α,β-unsaturated aldehydes; subsequent oxidation of the resulting allylic alcohols 7 using manganese(IV) oxide or, less effectively, treatment of the derived acetates 10 with Pd(0), results in direct formation of the novel triazolo[1,2]-benzodiazepines 9 and 11 by intramolecular addition of the pendant amino group.
