328587-59-3Relevant academic research and scientific papers
Chiral nonracemic C2-symmetry biphenyls by desymmetrization of 6,6',2,2'-tetramethoxy-1,1'-biphenyl
Delogu, Giovanna,Fabbri, Davide,Dettori, Maria Antonietta,Forni, Alessandra,Casalone, Gianluigi
, p. 4417 - 4427 (2000)
Regioselective bromination of the title biphenyl 1 at the 3 and 3' positions and simultaneous desymmetrization of the biphenyl has been achieved. Metal-halide exchange at the 3,3' positions facilitated the introduction of functional groups in good yield.
