3286-55-3

Usage

Uses

Used in Pharmaceutical Synthesis:
6-Chloro-4-amino-2-methoxypyrimidine is utilized as an intermediate in the synthesis of pharmaceuticals for its potential role in the development of new drugs. Its unique structural features contribute to the creation of diverse medicinal compounds.
Used in Agrochemical Synthesis:
In the agrochemical industry, 6-chloro-4-amino-2-methoxypyrimidine serves as a key intermediate in the production of pesticides, leveraging its reactivity to form effective compounds for agricultural applications.
Used in Organic Synthesis:
6-Chloro-4-amino-2-methoxypyrimidine is employed as a building block in organic synthesis, allowing for the construction of a wide range of organic compounds for various purposes, including research and commercial applications.
Used in Chemical Research:
6-CHLORO-4-AMINO-2-METHOXYPYRIMIDINE is also used in chemical research as a model or reagent to study reactions and mechanisms, furthering the understanding of organic chemistry and potentially leading to new discoveries and applications.

InChI:InChI=1/C5H6ClN3O/c1-10-5-8-3(6)2-4(7)9-5/h2H,1H3,(H2,7,8,9)

Upstream product

• 10132-07-7 4-amino-2,6-dichloropyrimidine 
• 124-41-4 sodium methylate 

Relevant academic research and scientific papers

SUBSTITUTED NITROGEN-CONTAINING SIX-MEMBERED AMINO-HETEROCYCLES AS VANILLOID-1 RECEPTOR ANTAGONISTS FOR TREATING PAIN

The present invention provides a compound of formula (I): Y-J-NH-Z wherein: Y is a quinoline or isoquinoline optionally substituted with one or two substituents independently chosen from hydroxy, halogen, haloC1-4alkyl, C1-4alkyl, C1-4alkoxy, haloC1-4alkoxy, nitro and amino; J is pyridine, pyridazine, pyrazine, pyrimidine or triazine optionally substituted with one or two substituents independently chosen from hydroxy, halogen, haloC1-4alkyl, C1-4alkyl, C3-5cycloalkyl, C1-4alkoxy, hydroxyC1-4alkyl, cyano, hydroxy, C1-4cycloalkoxy, C1-4alkylthio, haloC1-4alkoxy, nitro, Q, (CH2)pQ, NR2R3, -(CH2)pNR2R3 and -O(CH2)pNR2R3; wherein J is substituted at positions meta to each other by NH and Y; and Z is phenyl or pyridyl optionally substituted with one or two substituents independently selected from halogen, haloC1-4alkyl, C1-4alkyl, C1-4alkoxy, haloC1-4alkoxy, nitro and amino; Q is phenyl, a five-membered heterocyclic ring containing one, two, three or four heteroatoms chosen from O, N and S, at most one heteroatom being O or S, or a six-membered heterocyclic ring containing one, two or three nitrogen atoms, optionally substituted by C1-4alkyl; each R2 and R3 is chosen from H and C1-4alkyl, or R2 and R3, together with the nitrogen atom to which they are attached, may form a six-membered ring optionally containing an oxygen atom or a further nitrogen atom, which ring is optionally substituted by C1-4alkyl or Q; p is 1, 2 or 3; or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising it; its use in methods of therapy; use of it for manufacturing medicaments; and methods of using it to treat diseases requiring administration of a VR1 antagonist such as pain, cough, GERD and depression.